Caffeine acts on our nerve cells to wake us up. It turns out that it does so through a molecular signalling pathway that involves a positive feedback loop, boosting caffeine's effects from inside the cell.
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Vaugeois, JM. Positive feedback from coffee. Nature 418, 734–736 (2002). https://doi.org/10.1038/418734a
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DOI: https://doi.org/10.1038/418734a
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