Abstract
Two parallel studies using positron emission tomography, one conducted in neurological patients with brain lesions, the other in normal individuals, indicate that the normal process of retrieving words that denote concrete entities depends in part on multiple regions of the left cerebral hemisphere, located outside the classic language areas. Moreover, anatomically separable regions tend to process words for distinct kinds of items.
Similar content being viewed by others
References
Damasio, A. R. New Engl. J. Med. 326, 531–539 (1992).
Damasio, A. R., Damasio, H. & Van Hoesen, G. W. Neurology 32, 331–341 (1982).
Warrington, E. K. & McCarthy, R. A. Brain 106, 859–878 (1983).
Hart, J., Berndt, R. S. & Caramazza, A. Nature 316, 439–440 (1985).
Goodglass, H., Wingfield, A., Hyde, M. R. & Theurkauf, J. C. Cortex 22, 87–102 (1986).
Semenza, C. & Zettin, M. Nature 342, 678–679 (1989).
Damasio, A. R., Damasio, H., Tranel, D. & Brandt, J. P. Quant. Bio. 55, 1039–1047 (1990).
Damasio, A. R. & Damasio, H. Scient. Am. 267, 89–95 (1992).
Damasio, H. & Frank, R. Archs. Neurol. 49, 137–143 (1992).
Grabowski, T. J. et al. Hum. Brain Mapp. 2, 123–133 (1995).
Grabowski, T. J. et al. Hum. Brain Mapp. (in the press).
Smith, E. E. & Medin, D. L. Categories and Concepts (Harvard Univ. Press, Cambridge, MA, 1981).
Sergent, J., Ohta, S. & MacDonald, B. Brain 115, 15–36 (1992).
Nobre, A. C., Allison, T. & McCarthy, G. Nature 372, 260–263 (1994).
Raichle, M. E. et al. Cereb. Cort. 4, 8–26 (1994).
Martin, A., Haxby, J. V., Lalonde, F. M., Wiggs, C. L. & Ungerleider, L. G. Science 270, 102–105 (1995).
Ojemann, G. A. J. Neurosci. 11, 2281–2287 (1991).
Mazoyer, B. M. et al. J. cogn. Neurosci. 5, 467–479 (1993).
Petersen, S. E., Fox, P. T., Posner, M. I., Mintun, M. & Raichle, M. E. Nature 331, 585–589 (1988).
Damasio, A. R. & Tranel, D. Proc. natn. Acad. Sci. U.S.A. 90, 4957–4960 (1993).
Daniele, A., Giustolisi, L., Silveri, M. C., Colosimo, C. & Gainotti, G. Neuropsychologia 32, 1325–1341 (1994).
Hillis, A. E. & Caramazza, A. J. cogn. Neurosci. 7, 396–407.
Dehaene, S. NeuroReport 6, 2153–2157 (1995).
Levelt, W. J. M. Cognition 42, 1–22 (1992).
Garrett, M. Cognition 42, 143–180 (1992).
Damasio, A. R. Cognition 33, 25–62 (1989).
Damasio, A. R. & Damasio, H. in Large-Scale Neuronal Theories of the Brain (ed. Koch, C.) 61–74 (MIT Press, Cambridge, MA, 1994).
Kosslyn, S. M. Image and Brain (MIT Press, Cambridge, MA, 1994).
Tranel, D., Damasio, H., Damasio, A. R. & Brandt, J. P. Soc. Neurosci. Abstr. 21, 1497 (1995).
Perani, D. et al. Soc. Neurosci. Abstr. 21, 1498 (1995).
Carammaza, A. & Hillis, A. Nature 349, 788–790 (1991).
Hart, J. & Gordon, B. Nature 359, 60–64 (1992).
Hillis, A. E. & Caramazza, A. Brain 114, 2081–2094 (1991).
McCarthy, R. A. & Warrington, E. K. Nature 334, 428–430 (1988).
Martin, A., Wiggs, C. L., Ungerleider, L. G. & Haxby, J. V. Nature 379, 649–652 (1996).
McKenna, P. & Parry, R. Neuropsychol. Rehab. 4, 255–281 (1994).
Tranel, D., Damasio, H. & Damasio, A. R. J. cogn. Neurosci. 7, 425–432 (1995).
Albert, M. S., Butters, N. & Levin, J. A. Archs Neurol. 36, 211–216 (1979).
Snodgrass, J. G. & Vanderwart, M. J. exp. Psychol., hum. Learn. Mem. 6, 174–215 (1980).
Talairach, J. & Tournoux, P. Co-planar Stereotaxic Atlas of the Human Brain (Thieme Medical, New York, 1988).
Demonet, J.-F. et al. Brain 115, 1753–1768 (1992).
Ono, M., Kubik, S. & Abernathy, C. D. Atlas of the Cerebral Sulci (Thieme Medical, New York, 1990).
Damasio, H. et al. in Quantification of Brain Function. Tracer Kinetics and Image Analysis in Brain PET. (eds Uemura, K., Lassen, N. A., Jones, T. & Kanno, I) 465–473 (Elsevier, Amsterdam, 1993).
Herscovitch, P., Markham, J. & Raichle, M. E. J. nucl. Med. 24, 782–789 (1983).
Hichwa, R. A. et al. in Chemists' View of Imaging Centers (ed. Emran, A. M.) 401–417 (Plenum, New York, 1995).
Woods, R. P., Mazziotta, J. C. & Cherry, S. R. J. comput. assist. Tomogr. 17, 536–546 (1993).
Friston, K. J., Frith, C. D., Liddle, P. F. & Frackowiak, R. S. J. J. Cereb. Blood Flow Metab. 11, 690–699 (1991).
Worsley, K. J. Adv. Appl. Prob. 26, 13–42 (1994).
Friston, K. J., Worsley, K. J., Frackowiak, R. S. J., Mazziotta, J. C. & Evans, A. C. Hum. Brain Mapp. 1, 210–220 (1994).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Damasio, H., Grabowski, T., Tranel, D. et al. A neural basis for lexical retrieval. Nature 380, 499–505 (1996). https://doi.org/10.1038/380499a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/380499a0
- Springer Nature Limited
This article is cited by
-
Immediate neural impact and incomplete compensation after semantic hub disconnection
Nature Communications (2023)
-
Proper and common names in the semantic system
Brain Structure and Function (2023)
-
Modulation of proper name recall by transcranial direct current stimulation of the anterior temporal lobes
Scientific Reports (2022)
-
Convergence of heteromodal lexical retrieval in the lateral prefrontal cortex
Scientific Reports (2021)
-
Reverse-engineering the cortical architecture for controlled semantic cognition
Nature Human Behaviour (2021)