Abstract
Maternal hunchback activity suppresses the genetic pathway for abdomen formation in the Drosophila embryo. The active component of the posterior group of maternal genes, nanos, acts as a specific represser of hunchback in the posterior region. Absence of both repressors results in normal embryos, indicating that posterior segmentation may not directly require maternal determinants.
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References
Nüsslein-Volhard, C. C., Frohnhöfer, H. G. & Lehmann, R. Science 238, 1675–1681 (1987).
Fröhnhofer, H. G. & Nüsslein-Volhard, C. Nature 324, 120–125 (1986).
Driever, W. & Nüsslein-Volhard, C. Cell 54, 83–93 (1988).
Driever, W. & Nüsslein-Volhard, C. Cell 54, 95–104 (1988).
Nüsslein-Volhard, C. & Wieschaus, E. Nature 287, 795–801 (1980).
Akam, M. Development 101, 1–22 (1987).
Ingham, P. W. Nature 335, 25–34 (1988).
Schüppach, T. & Wieschaus, E. Wilhelm Roux's Arch. Dev. Biol. 195, 302–317 (1986).
Lehmann, R. & Nüsslein-Volhard, C. Cell 47, 141–152 (1986).
Lehmann, R. & Nüsslein-Volhard, C. Nature 329, 167–170 (1987).
Lehmann, R. Development Suppl. 104, 17–27 (1988).
Sander, K. & Lehmann, R. Nature 335, 68–70 (1988).
Tautz, D. Nature 332, 281–284 (1988).
Lehmann, R. & Nüsslein-Volhard, C. Devl. Biol. 119, 402–417 (1987).
Tautz, D. et al. Nature 337, 382–389 (1987).
Bender, M., Horikami, S., Cribbs, D. & Kaufmann, T. C. Dev. Gene. 9, 715–732 (1988).
Schröder, C., Tautz, D., Seifert, E. & Jäckie, H. EMBO J. 7, 2881–2887 (1988).
Carroll, S. B. & Scott, M. P. Cell 43, 47–47 (1985).
Krause, H. M., Klemenz, R. & Gehring, W. J. Genes Dev. 2, 1021–1036 (1988).
Martinez-Arias, A. & Lawrence, P. A. Nature 313, 639–642 (1985).
Busson, D., Gans, M., Komitopoulou, K. & Masson, M. Genetics 105, 309–325 (1983).
Akam, M. & Struhl, G. Nature, 338, 646–648 (1989).
Nauber, U. et al. Nature 336, 489–492 (1988).
Mahaffey, J. W. & Kaufman, T. C. in Developmental genetics of higher organisms (ed. Malacinski, G. M.) 329–360 (Macmillan, New York, 1988).
Bender, M., Turner, F. R. & Kaufmann, T. C. Devl Biol. 119, 418–432 (1987).
White, R. A. H. & Lehmann, R. Cell 47, 311–321 (1986).
Tear, G., Bate, C. M. & Martinez-Arias, A. Development Suppl. 104, 135–145 (1988).
Harding, K. & Levine, M. EMBO J. 7, 205–214 (1988).
Sander, K. Adv. Insect Physiol. 12, 125–238 (1976).
Shapira, S. K. et al. Gene 25, 71–78 (1983).
Rosenberg, U. B. et al. Nature 319, 336–339 (1986).
Rubin, G. M. & Spradling, A. C. Nucleic Acids Res. 11, 6341 (1983).
Foe, V. E. & Alberts, B. M. J. Cell Sci. 61, 31–70 (1983).
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Hülskamp, M., Schröder, C., Pfeifle, C. et al. Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene. Nature 338, 629–632 (1989). https://doi.org/10.1038/338629a0
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DOI: https://doi.org/10.1038/338629a0
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