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An unusual transposon with long terminal inverted repeats in the sea urchin Strongylocentrotus purpuratus

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Abstract

A 3-kilobase DNA segment characteristic of a transposable element was found within a histone H2B pseudogene in a higher eukaryote, the sea urchin Strongylocentrotus purpuratus. The inserted segment (TU1) is flanked by 8-base pair (bp) direct repeats of the H2B sequence. TU1 has long terminal inverted repeats ∼840 bp long with an outer domain of 15-bp tandem repeats and a non-repeating inner domain, and is a member of a heterogeneous family of transposable elements. TU1 differs from most previously characterized eukaryotic transposable elements with terminal direct repats, but resembles the foldback transposon family in Drosophila.

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Author information

Author notes

  1. Joel Weinthal

    Present address: Columbia University College of Physicians and Surgeons, New York, New York, 10027, USA

  2. Robert Maxson

    Present address: Department of Biochemistry, University of Southern California School of Medicine, Los Angeles, California, 90089, USA

  3. Alex Mauron

    Present address: Department of Biochemistry, University of Geneva, Geneva, Switzerland

Authors and Affiliations

  1. The MEDIGEN Project, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA

    Dan Liebermann, Joel Weinthal, Robert Maxson, Alex Mauron & Larry Kedes

  2. Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305, USA

    Barbara Hoffman-Liebermann & Stanley N. Cohen

  3. Veterans Administration Medical Center, Palo Alto, California, 94304, USA

    Dan Liebermann, Joel Weinthal, Robert Maxson, Alex Mauron & Larry Kedes

  4. Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, 10461, USA

    Geoffrey Childs

Authors
  1. Dan Liebermann
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  2. Barbara Hoffman-Liebermann
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  3. Joel Weinthal
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  4. Geoffrey Childs
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  5. Robert Maxson
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  6. Alex Mauron
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  7. Stanley N. Cohen
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  8. Larry Kedes
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Liebermann, D., Hoffman-Liebermann, B., Weinthal, J. et al. An unusual transposon with long terminal inverted repeats in the sea urchin Strongylocentrotus purpuratus. Nature 306, 342–347 (1983). https://doi.org/10.1038/306342a0

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  • DOI: https://doi.org/10.1038/306342a0

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