Skip to main content
SpringerLink
Log in

Nucleosome assembly

  • Review Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Histones and DNA can spontaneously associate to form the nucleosome subunits of eukaryotic chromatin, but two proteins which occur in the eukaryotic nucleus can facilitate nucleosome assembly and greatly extend the conditions which permit assembly to occur. Recently several laboratories have reported new experimental systems which help to analyse, reconstruct and exploit the cellular mechanisms of chromatin assembly.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Kornberg, R. D. A. Rev. Biochem. 46, 931–954 (1977).

    CAS  Google Scholar 

  2. Felsenfeld, G. Nature 271, 115–122 (1978).

    CAS  PubMed  ADS  Google Scholar 

  3. Chambon, P. Cold Spring Harb. Symp. quant. Biol. 42, 1209–1234 (1978).

    CAS  PubMed  Google Scholar 

  4. Lilley, D. M. J. & Pardon, J. F. A. Rev. Genet. 13, 197–233 (1979).

    CAS  Google Scholar 

  5. Finch, J. T. et al. Nature 269, 29–36 (1977).

    CAS  PubMed  ADS  Google Scholar 

  6. Thoma, F., & Klug, A. J. Cell biol. 83, 403–427 (1979).

    CAS  PubMed  Google Scholar 

  7. Simpson, R. T. Biochemistry 17, 5524–5531 (1978).

    CAS  PubMed  Google Scholar 

  8. Mayfield, J. E., Serunian, L. A., Silver, L. M. & Elgin, S. C. R. Cell 14, 539–544 (1978).

    CAS  PubMed  Google Scholar 

  9. Elgin, S. C. R. & Weintraub, H. A. Rev. Biochem. 44, 725–774 (1975).

    CAS  Google Scholar 

  10. Ruiz-Carrillo, A., Jorcano, J. L., Eder, G. & Lurtz, R. Proc. natn. Acad. Sci. U.S.A. 76, 3284–3288 (1979).

    CAS  ADS  Google Scholar 

  11. Stein, A., Whitlock, J.P. & Bina, M. Proc. natn. Acad. Sci. U.S.A. 76, 5000–5004 (1979).

    CAS  ADS  Google Scholar 

  12. Laskey, R. A., Honda, B. M., Mills, A. D. & Finch, J. T. Nature 275, 416–420 (1978).

    CAS  PubMed  ADS  Google Scholar 

  13. Germond, J.E., Rouviere-Yaniv, J., Yaniv, M. & Brutlag, D. Proc. natn. Acad. Sci. U.S.A. 76, 3779–3783 (1979).

    CAS  ADS  Google Scholar 

  14. Laskey, R. A., Mills, A. D. & Morris, N. R. Cell 10, 237–243 (1977).

    CAS  PubMed  Google Scholar 

  15. Baldi, M. I., Mattoccia, E. & Tocchini-Valentini, G. P. Proc. natn. Acad. Sci. U.S.A. 75, 4873–4876 (1978).

    CAS  ADS  Google Scholar 

  16. Nelson, T., Hsieh, T.-S. & Brutlag, D. Proc. natn. Acad. Sci. U.S.A. 76, 5510–5514 (1979).

    CAS  ADS  Google Scholar 

  17. Axel, R., Melchior, W., Sollner-Webb, B. & Felsenfeld, G. Proc. natn. Acad. Sci. U.S.A. 71, 4101–4105 (1974).

    CAS  ADS  Google Scholar 

  18. Oudet, P., Gross-Bellard, M. & Chambon, P. Cell 4, 281–300 (1975).

    CAS  PubMed  Google Scholar 

  19. Germond, J. E., Hirt, B., Oudet, P., Gross-Bellard, M. & Chambon, P. Proc. natn. Acad. Sci. U.S.A. 72, 1843–1847 (1975).

    CAS  ADS  Google Scholar 

  20. Camerini-Otero, R. D., Sollner-Webb, B. & Felsenfeld, G. Cell 8, 333–347 (1976).

    CAS  PubMed  Google Scholar 

  21. Steinmetz, M., Streeck, R. E. & Zachau, H. G. Eur. J. Biochem. 83, 615–628 (1978).

    CAS  PubMed  Google Scholar 

  22. Champoux, J.J. A. Rev. Biochem. 47, 449–479 (1978).

    CAS  Google Scholar 

  23. Laskey, R.A., Honda, B.M., Mills, A.D., Harland, R.M. & Earnshaw, W.C. in Eukaryotic Gene Regulation, ICN-UCLA Symposium 14 (eds Maniatis, T., Axel, R. & Fox, C. F. 551–559) (AcademiC., New York, 1979).

    Google Scholar 

  24. Krohne, G. & Franke, W. Proc. natn. Acad. Sci. U.S.A. 77, 1034–1038 (1980).

    CAS  ADS  Google Scholar 

  25. Krohne, G. & Franke, W. Expl. Cell Res. (in the press).

  26. Mills, A. D., Laskey, R. A., Black, P. & De Robertis, E. M. J. molec. Biol. 139, 561–568 (1980).

    CAS  PubMed  Google Scholar 

  27. Earnshaw, W. C., Honda, B. M., Laskey, R. A. & Thomas, J. O. Cell (in the press).

  28. Voordouw, G. & Eisenberg, H. Nature 273, 446–448 (1978).

    CAS  PubMed  ADS  Google Scholar 

  29. Stein, A. J. molec. Biol. 130, 103–104

  30. Wyllie, A. H., Laskey, R. A., Finch, J. & Gurdon, J. B. Devl. Biol. 64, 178–188 (1978).

    CAS  Google Scholar 

  31. Adamson, E. D. & Woodland, H. R. J. molec. Biol. 88, 263–285 (1974).

    CAS  PubMed  Google Scholar 

  32. Woodland, H. R. & Adamson, E. D. Devl. Biol. 57, 118–135 (1977).

    CAS  Google Scholar 

  33. Worcel, A., Han, S. & Wong, M. L. Cell 15, 969–977 (1978).

    CAS  PubMed  Google Scholar 

  34. Senshu, T., Fukada, M. & Ohashi, M. J. Biochem. (Japan) 84, 985–988 (1978).

    CAS  Google Scholar 

  35. Cremisi, C., Chestier, A. & Yaniv, M. Cell 12, 947–951 (1977).

    CAS  PubMed  Google Scholar 

  36. Rabinowitz, M. J. Morphol. 69, 1–49 (1941).

    Google Scholar 

  37. Blumenthal, A. B., Kriegstein, H.J. & Hogness, D.S. Cold Spring Harb. Symp. quant. Biol. 38, 205–233 (1973).

    Google Scholar 

  38. Louie, A.J. & Dixon, G. H. Proc. natn. Acad. Sci. U.S.A. 69, 1975–1979 (1972).

    CAS  ADS  Google Scholar 

  39. Ruiz-Carrillo, A., Wangh, L. J. & Allfrey, V. Science 190, 117–128 (1975).

    CAS  PubMed  ADS  Google Scholar 

  40. Jackson, V., Shires, A., Tanphaichitr, N. & Chalkley, R. J. molec. Biol. 104, 471–483 (1976).

    CAS  PubMed  Google Scholar 

  41. Hewish, D. R. & Burgoyne, L. A. Biochem. biophys. Res. Commun. 52, 504–510 (1973).

    CAS  Google Scholar 

  42. Noll, M., Nature 251, 249–251 (1974).

    CAS  ADS  Google Scholar 

  43. Morris, N. R. Cell 9, 627–632 (1976).

    CAS  PubMed  Google Scholar 

  44. Noll, M., Cell 8, 349–355 (1976).

    CAS  PubMed  Google Scholar 

  45. Thomas, J.O. & Thompson, R.J. Cell 10, 633–640 (1977).

    CAS  PubMed  Google Scholar 

  46. Compton, J.L., Bellard, M. & Chambon, P. Proc. natn. Acad. Sci. U.S.A. 73, 4382–4386 (1976).

    CAS  ADS  Google Scholar 

  47. Spadafora, C., Bellard, M., Compton, J.L. & Chambon, P. FEBS Lett. 69, 281–285 (1976).

    CAS  PubMed  Google Scholar 

  48. Woodland, H. R. Devl Biol. 68, 360–370 (1979).

    CAS  Google Scholar 

  49. Ponder, B. A.J. & Crawford, L. V. Cell 11, 35–49 (1977).

    CAS  PubMed  Google Scholar 

  50. Varshavsky, A.J., Sundin, O. & Bohn, M. Cell 16, 453–466 (1979).

    CAS  PubMed  Google Scholar 

  51. Waldeck, W., Föhring, B., Chowdhury, K., Gruss, P. & Sauer, G., Proc. natn. Acad. Sci. U.S.A. 75, 5964–5968 (1978).

    CAS  ADS  Google Scholar 

  52. Scott, W. A. & Wigmore, D.J. Cell 15, 1511–1518 (1978).

    CAS  PubMed  Google Scholar 

  53. Wittig, B. & Wittig, S. Cell 18, 1173–1183 (1979).

    CAS  PubMed  Google Scholar 

  54. Wu, C., Bingham, P.M., Livak, K. J., Holmgren, R. & Elgin, S. C. R. Cell 16, 797–806 (1979).

    CAS  PubMed  Google Scholar 

  55. Musich, P. R., Maio, J.J. & Brown, F.L. J. molec. Biol. 117, 637–655 (1977).

    PubMed  Google Scholar 

  56. Seale, R. L. Nature 225, 247–249 (1975).

    ADS  Google Scholar 

  57. Seale, R. L. Cold Spring Harb. Symp. quant. Biol. 42, 433–438 (1978).

    CAS  PubMed  Google Scholar 

  58. McKnight, S. L. & Miller, O.L. Jr Cell 12, 795–804 (1977).

    CAS  PubMed  Google Scholar 

  59. Levy, A. & Jakob, K. M. Cell 14, 259–267 (1978).

    CAS  PubMed  Google Scholar 

  60. Weintraub, H. Nucleic Acids Res. 7, 781–792 (1979).

    CAS  PubMed  PubMed Central  Google Scholar 

  61. Leffak, M., Grainger, R. & Weintraub, H. Cell 12, 837–845 (1977).

    CAS  PubMed  Google Scholar 

  62. Seale, R. L. Cell 9, 423–429 (1976).

    CAS  PubMed  Google Scholar 

  63. Hancock, R. Proc. natn. Acad. Sci. U.S.A. 75, 2130–2134 (1978).

    CAS  ADS  Google Scholar 

  64. Jackson, V., Granner, D. & Chalkley, R. Proc. natn. Acad. Sci. U.S.A. 73, 2266–2269 (1976).

    CAS  ADS  Google Scholar 

  65. Riley, D. & Weintraub, H. Proc. natn. Acad. Sci. U.S.A. 76, 328–332 (1979).

    CAS  ADS  Google Scholar 

  66. Hand, R. Cell 15, 317–325 (1978).

    CAS  PubMed  Google Scholar 

  67. Seidman, M. M., Levine, A. J. & Weintraub, H. Cell 18, 439–449 (1979).

    CAS  PubMed  Google Scholar 

  68. Kornberg, R. D. Science 184, 868–871 (1974).

    CAS  PubMed  ADS  Google Scholar 

  69. Garel, A. & Axel, R. Proc. natn. Acad. Sci. U.S.A. 73, 3966–3970 (1976).

    CAS  ADS  Google Scholar 

  70. Weintraub, H. & Groudine, M. Science 93, 848–853 (1976).

    ADS  Google Scholar 

  71. Gottesfeld, J. M., Bagi, G., Berg, B. & Bonner, J. Biochemistry 15, 2472–2483 (1976).

    CAS  PubMed  Google Scholar 

  72. Garel, A., Zolan, M. & Axel, R. Proc. natn. Acad. Sci. U.S.A. 74, 4867–4871 (1977).

    CAS  ADS  Google Scholar 

  73. Flint, S.J. & Weintraub, H. M. Cell 12, 783–794 (1977).

    CAS  PubMed  Google Scholar 

  74. Levy, W.B. & Dixon, G. Nucleic Acids Res. 5, 4155–4163 (1978).

    CAS  PubMed  PubMed Central  Google Scholar 

  75. Weisbrod, S. & Weintraub, H. Proc. natn. Acad. Sci. U.S.A. 76, 630–634 (1979).

    CAS  ADS  Google Scholar 

  76. Goodwin, G. H., Walker, J.M. & Johns, E. W. in The Cell Nucleus Vol. 6 (ed. Busch, H.) pp. 181–219 (1978).

    Google Scholar 

  77. Weisbrod, S., Groudine, M. & Weintraub, H. Cell 19, 289–301 (1980).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    Ronald A. Laskey & William C. Earnshaw

Authors
  1. Ronald A. Laskey
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. William C. Earnshaw
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Laskey, R., Earnshaw, W. Nucleosome assembly. Nature 286, 763–767 (1980). https://doi.org/10.1038/286763a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/286763a0

  • Springer Nature Limited

This article is cited by

Search

Navigation