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A mouse α-globin-related pseudogene lacking intervening sequences

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Abstract

A mouse α-globin-related pseudogene (ψα30.5) completely lacks intervening sequences, and could not code for a functional globin polypeptide because of frameshifts. The widespread occurrence of globin pseudogenes in other species suggests that they are not ‘dead’ genes but may be important in controlling globin expression.

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Author notes

  1. Philip W. Tucker

    Present address: Department of Biochemistry, University of Mississippi Medical Center, Jackson, Mississippi, 39216

Authors and Affiliations

  1. Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin, 53706

    Elio F. Vanin, Gregory I. Goldberg, Philip W. Tucker & Oliver Smithies

Authors
  1. Elio F. Vanin
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  2. Gregory I. Goldberg
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  3. Philip W. Tucker
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  4. Oliver Smithies
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Vanin, E., Goldberg, G., Tucker, P. et al. A mouse α-globin-related pseudogene lacking intervening sequences. Nature 286, 222–226 (1980). https://doi.org/10.1038/286222a0

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  • DOI: https://doi.org/10.1038/286222a0

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