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Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA

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Abstract

The nucleosome subunits of chromatin are assembled from histones and DNA by an acidic protein which binds histones. The nucleosome assembly protein has been identified and purified from eggs of Xenopus laevis.

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Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK

    R. A. Laskey, B. M. Honda, A. D. Mills & J. T. Finch

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  1. R. A. Laskey
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  2. B. M. Honda
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  3. A. D. Mills
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  4. J. T. Finch
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Laskey, R., Honda, B., Mills, A. et al. Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA. Nature 275, 416–420 (1978). https://doi.org/10.1038/275416a0

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