Abstract
THE triethylammonium salt of the dinucleoside phosphate, thymidylyl-3′, 5′-deoxyadenosine (TpdA) forms helical structures when aqueous solutions are allowed to evaporate1. There are some similarities between the X-ray diffraction patterns from TpdA and those from poly(dA-dT)–poly(dA-dT), and we originally thought that the structures might be similar1. But when the structure for poly(dA-dT)–poly(dA-dT) was proposed2 it was apparent that the TpdA structure was not of the same kind. This, together with the fact that we had obtained more detailed X-ray diffraction patterns from better oriented TpdA specimens, led us to consider the different molecular model for TpdA which we describe here.
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WILSON, H., AL-MUKHTAR, J. Structure of thymidylyl-3′, 5′-deoxyadenosine. Nature 263, 171–172 (1976). https://doi.org/10.1038/263171a0
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DOI: https://doi.org/10.1038/263171a0
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