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Messenger RNA for the coat protein of tobacco mosaic virus

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Abstract

TMV RNA is not an efficient template for translation of the viral coat protein, in spite of containing nucleo-tide sequences coding for the protein. Efficient translation requires the prior synthesis within infected cells of a smaller RNA carrying only a portion of the information encoded in the whole genome.

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References

  1. Caspar, D. L. D., Adv. Protein Chem., 18, 37–121 (1963).

    CAS  PubMed  Google Scholar 

  2. Wittman, H. G., and Wittman-Liebold, B., Cold Spring Harb. Symp. Quant. Biol., 31, 163–172 (1966).

    Google Scholar 

  3. Funatsu, G., and Fraenkel-Conrat, H., Biochemistry, 3, 1356–1362 (1964).

    CAS  PubMed  Google Scholar 

  4. Guilley, H., Jonard, G., Richards, K. E., and Hirth, L., Eur. J. Biochem., 54, 135–153 (1975).

    CAS  PubMed  Google Scholar 

  5. Tsugita, A., Fraenkel-Conrat, H., Nirenberg, M. W., and Matthaei, J. H., Proc. natn. Acad. Sci. U.S.A., 48, 846–853 (1962).

    ADS  CAS  Google Scholar 

  6. Efron, D., and Marcus, A., Virology, 53, 343–348 (1973).

    CAS  PubMed  Google Scholar 

  7. Knowland, J., Genetics, 78, 383–394 (1974).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Aach, H. G., Funatsu, G., Nirenberg, M. W., and Fraenkel-Conrat, H., Biochemistry, 3, 1362–1366 (1964).

    CAS  PubMed  Google Scholar 

  9. Schwartz, J. H., J. molec. Biol., 30, 309–322 (1967).

    CAS  PubMed  Google Scholar 

  10. Roberts, B. E., Mathews, M. B., and Bruton, C. J., J. molec. Biol., 80, 733–742 (1973).

    CAS  PubMed  Google Scholar 

  11. Roberts, B. E., Paterson, B. M., and Sperling, R., Virology, 59, 307–313 (1974).

    CAS  PubMed  Google Scholar 

  12. Sakai, F., and Takebe, I., Virology, 62, 426–433 (1974).

    CAS  PubMed  Google Scholar 

  13. Paterson, R., and Knight, C. A., Virology, 64, 10–22 (1975).

    CAS  PubMed  Google Scholar 

  14. Siegel, A., Zaitlin, M., and Duda, C. T., Virology, 53, 75–83 (1973).

    CAS  PubMed  Google Scholar 

  15. Beachy, R. N., and Zaitlin, M., Virology, 63, 84–97 (1975).

    CAS  PubMed  Google Scholar 

  16. Roberts, B. E., and Paterson, B. M., Proc. natn. Acad. Sci. U.S.A., 70, 2330–2334 (1974).

    ADS  Google Scholar 

  17. Anderson, C. W., Baum, P. R., and Gesteland, R. F., J. Virol., 12, 241–252 (1973).

    CAS  PubMed  PubMed Central  Google Scholar 

  18. Bonner, W. M., and Laskey, R. A., Eur. J. Biochem., 46, 83–88 (1974).

    CAS  PubMed  Google Scholar 

  19. Peacock, A. C., and Dingman, C. W., Biochemistry, 7, 668–674 (1968).

    CAS  PubMed  Google Scholar 

  20. Dahlberg, A. E., Dingman, C. W., and Peacock, A. C., J. molec. Biol., 41, 139–147 (1969).

    CAS  PubMed  Google Scholar 

  21. Garfin, D. E., thesis, Univ. California (1972); Garfin, D. E., Mandels, S., Virology, 64, 388–399 (1975).

    Google Scholar 

  22. Schramm, G., Schumacher, G., and Zillig, W., Z. Naturf., 10 b, 481–492 (1955).

    Google Scholar 

  23. Perham, R. N., J. molec. Biol., 45, 439–441 (1969).

    CAS  PubMed  Google Scholar 

  24. Perham, R. N., and Wilson, T. M. A., FEBS Lett., 62, 11–15 (1976).

    CAS  PubMed  Google Scholar 

  25. Oberg, B., and Philipson, L., Biochem. biophys. Res. Commun., 48, 927–932 (1972).

    CAS  PubMed  Google Scholar 

  26. Guilley, H., Jonard, G., and Hirth, L., Proc. natn. Acad. Sci. U.S.A., 72, 864–868 (1975).

    ADS  CAS  Google Scholar 

  27. Kado, C. I., and Knight, C. A., J. molec. Biol., 36, 15–23 (1968).

    CAS  PubMed  Google Scholar 

  28. Richards, K. E., Morel, M. C., Nicolaieff, A., Lebeurier, G., and Hirth, L., Biochimie, 57, 749–755 (1975).

    CAS  PubMed  Google Scholar 

  29. Brishammer, S., and Junnti, N., Virology, 59, 245–253 (1974).

    Google Scholar 

  30. Zaitlin, M., Duda, C. T., and Petti, M. A., Virology, 53, 300–311 (1973).

    CAS  PubMed  Google Scholar 

  31. Durham, A. C. H., Finch, J. T., and Klug, A., Nature new Biol., 229, 37–42 (1971).

    CAS  PubMed  Google Scholar 

  32. Butler, P. J. G., and Klug, A., Nature new Biol., 229, 47–50 (1971).

    CAS  PubMed  Google Scholar 

  33. Caspar, D. L. D., and Klug, A., Cold Spring Harb. Symp. Quant. Biol., 27, 1–24 (1962).

    CAS  PubMed  Google Scholar 

  34. Rueckert, R. R., in Comparative Virology (edit. by Maramorosch, K., and Kurstack, E.), 255–306 (Academic, New York, 1971).

    Google Scholar 

  35. Fiers, W., et al., Nature, 256, 273–278 (1975).

    ADS  CAS  PubMed  Google Scholar 

  36. Shih, D. S., Lane, L. C., and Kaesberg, P., J. molec. Biol., 64, 353–362 (1972).

    CAS  PubMed  Google Scholar 

  37. Shih, D. S., and Kaesberg, P., Proc. natn. Acad. Sci. U.S.A., 70, 1799–1803 (1973).

    ADS  CAS  Google Scholar 

  38. DasGupta, R., Shih, D. S., Saris, C., and Kaesberg, P., Nature, 256, 624–628 (1975).

    ADS  CAS  PubMed  Google Scholar 

  39. Both, G. W., Banerjee, A. K., and Shatkin, A. J., Proc. natn. Acad. Sci. U.S.A., 72, 1189–1193 (1975).

    ADS  CAS  Google Scholar 

  40. Zimmern, D., Nucleic Acid Res., 2, 1189–1201 (1975).

    CAS  PubMed  PubMed Central  Google Scholar 

  41. Simmons, D. T., and Strauss, J. H., J. molec. Biol., 86, 397–409 (1974).

    CAS  PubMed  Google Scholar 

  42. Clegg, J. C. S., and Kennedy, S. I. T., Eur. J. Biochem., 53, 175–183 (1975).

    CAS  Google Scholar 

  43. Prives, C. L., Aviv, H., Gilboa, E., Revel, M., and Winocour, E., Cold Spring Harb. Symp. Quuat. Biol., 39, (1) 309–316 (1975).

    Google Scholar 

  44. Barrell, B. G., in Procedures in Nucleic Acid Research (edit. by Cantoni, G. L., and Davies, D. R.), 751–779 (Harper and Row, New York, 1971).

    Google Scholar 

  45. Schimke, R. T., et al., in Methods in Enzymology, 30 (edit. by Moldave, K., and Grossman, L.), 631–648 (Academic, New York, 1974).

    Google Scholar 

  46. Ritschard, W. J., J. Chromatog., 16, 327–333 (1964).

    CAS  Google Scholar 

  47. Vandekerkhove, J., and Van Montague, M., Eur. J. Biochem., 44, 279–288 (1974).

    Google Scholar 

  48. Knowland, J., Hunter, T., Hunt, T., and Zimmern, D., Proc. INSERM-EMBO Colloquium In vitro Transcription and Translation of Viral Genomes, INSERM, 47, 211–216 (1975).

    CAS  Google Scholar 

  49. Bruening, G., Beachy, R. N., Scalla, R., and Zaitlin, M., Virology, (in the press).

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Author information

Author notes

  1. Tony R. Hunter

    Present address: Salk Institute, PO Box 1809, San Diego, California, 92112

  2. John Knowland

    Present address: Department of Anatomy, Medical School, Bristol, BS8 1TD, UK

Authors and Affiliations

  1. Department of Biochemistry, Tennis Court Road, Cambridge, CB2 1QW, UK

    Tony R. Hunter & Tim Hunt

  2. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2HQ, UK

    John Knowland & David Zimmern

Authors
  1. Tony R. Hunter
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  2. Tim Hunt
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  3. John Knowland
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  4. David Zimmern
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Hunter, T., Hunt, T., Knowland, J. et al. Messenger RNA for the coat protein of tobacco mosaic virus. Nature 260, 759–764 (1976). https://doi.org/10.1038/260759a0

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  • DOI: https://doi.org/10.1038/260759a0

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