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Insulin unmasks latent sodium pump sites in frog muscle

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Abstract

INSULIN stimulates the movement across the cell membrane of a variety of substances such as glucose1, amino acids2, and alkali cations Na+ and K+ (refs 3 and 4). All these substances move through specific membrane sites but it is not known whether insulin stimulates transport by increasing the available number of sites or by increasing the efficiency with which the sites operate.

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References

  1. Levine, R., Goldstein, M., Klein, S., and Huddlestun, B., J. biol. Chem., 179, 985 (1949).

    CAS  PubMed  Google Scholar 

  2. Manchester, K. L., and Young, F. G., Biochem. J., 75, 487 (1960).

    Article  CAS  Google Scholar 

  3. Zierler, K. L., Am. J. Physiol., 198, 1066 (1960).

    CAS  PubMed  Google Scholar 

  4. Moore, R. O., J. Physiol., Lond., 232, 23 (1973).

    Article  ADS  CAS  Google Scholar 

  5. Schatzmann, H. J., Helv. physiol. pharmac. Acta, 11, 346 (1953).

    CAS  Google Scholar 

  6. Glynn, I. M., Pharmac. Rev., 16, 381 (1971).

    Google Scholar 

  7. Horowicz, P., Taylor, J. W., and Waggoner, D. M., J. gen. Physiol., 55, 401 (1970).

    Article  CAS  Google Scholar 

  8. Keynes, R. D., and Swan, R. C., J. Physiol., Lond., 147, 591 (1959).

    Article  CAS  Google Scholar 

  9. García, M., Leblanc, G., and Erlij, D., Pflügers Arch. ges. Physiol., 311, 278 (1969).

    Article  Google Scholar 

  10. Keynes, R. D., and Steinhardt, R. A., J. Physiol., Lond., 198, 581 (1968).

    Article  CAS  Google Scholar 

  11. Erlij, D., and Leblanc, G., J. Physiol., Lond., 214, 327 (1971).

    Article  CAS  Google Scholar 

  12. Erlij, D., and Elizalde, A., Biochim. biophys. Acta, 345, 49 (1974).

    Article  CAS  Google Scholar 

  13. Abeles, A. L., J. gen. Physiol., 54, 268 (1969).

    Article  CAS  Google Scholar 

  14. Baker, P. F., and Willis, J. S., J. Physiol., Lond., 224, 441 (1972).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Departamento de Biologia Celular, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Apartado Postal 14-740, Mexico, DF, 14

    S. GRINSTEIN & D. ERLIJ

Authors
  1. S. GRINSTEIN
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  2. D. ERLIJ
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GRINSTEIN, S., ERLIJ, D. Insulin unmasks latent sodium pump sites in frog muscle. Nature 251, 57–58 (1974). https://doi.org/10.1038/251057a0

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  • DOI: https://doi.org/10.1038/251057a0

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