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Lymphocyte separation from blood

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Abstract

MUCH attention has been focussed on the role of lymphocytes in the immune response of the tumour-bearing host. To study the cytotoxic effects of lymphocytes from rabbits bearing VX2 tumours towards the tumour cells in vitro, a suitable method for obtaining lymphocytes from peripheral blood was sought. With the recognition that both T and B lymphocyte populations are heterogeneous, and have different properties and functions which modulate each other's activities1, the question of cell yield assumes importance in lymphocyte preparations. The method of choice should also be simple and rapid.

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Authors and Affiliations

  1. Cancer Research Unit, Department of Clinical Biochemistry, Royal Victoria Infirmary, Newcastle-upon-Tyne

    S. A. SHAH & J. A. DICKSON

Authors
  1. S. A. SHAH
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  2. J. A. DICKSON
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SHAH, S., DICKSON, J. Lymphocyte separation from blood. Nature 249, 168–169 (1974). https://doi.org/10.1038/249168a0

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  • DOI: https://doi.org/10.1038/249168a0

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