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Suppression of Mouse Antibody Producing Spleen Cells by Various Interferon Preparations

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Abstract

POLYRIBOINOSINIC acid: polyribocytidylic acid [poly (rI)·poly (rC)], endotoxin, polycarboxylate plastics or polysaccharides, and other polyanions induce interferon production (see reviews ref. 1 and 2). They also enhance antibody production3,4, cell-mediated immunity5, and reticuloendothelial activity4,6. It is not yet clear whether or not any of these latter effects are mediated through the action of interferon.

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Authors and Affiliations

  1. Division of Infectious Diseases, Department of Medicine, Stanford University School of Medicine, Stanford, California, 94305

    THOMAS J. CHESTER

  2. Department of Microbiology, Medical College of Pennsylvania, Philadelphia, Pennsylvania, 19129

    KURT PAUCKER

  3. Division of Infectious Diseases, Department of Medicine, Stanford University School of Medicine, Stanford, California, 95305

    THOMAS C. MERIGAN

Authors
  1. THOMAS J. CHESTER
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  2. KURT PAUCKER
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  3. THOMAS C. MERIGAN
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CHESTER, T., PAUCKER, K. & MERIGAN, T. Suppression of Mouse Antibody Producing Spleen Cells by Various Interferon Preparations. Nature 246, 92–94 (1973). https://doi.org/10.1038/246092a0

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  • DOI: https://doi.org/10.1038/246092a0

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