Skip to main content
SpringerLink
Log in

How was the Sdic gene fixed?

  • Scientific Correspondence
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Nurminsky et al.1 have described a new gene of Drosophila melanogaster, termed Sdic (for sperm-specific dynein, intermediate chain), which appears to have evolved recently as a result of fusion between duplicated copies of two adjacent genes, Cdic and AnnX. They consider that the low DNA sequence variation at Sdic and Cdic is consistent with a recent ‘selective sweep’ associated with the fixation of Sdic. (In a selective sweep, new favourable mutations are incorporated so rapidly that linked alleles can ‘hitchhike’ and become fixed.) Here we evaluate the evidence for this proposal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Nurminsky, D. I., Nurminskaya, M. V., De Aguiar, D. & Hartl, D. L. Nature 396, 572–575 (1998).

    Google Scholar 

  2. 2.Schalet, A. & Lefevre, G. in The Genetics and Biology ofDrosophila (eds Ashburner, M. & Novitski, E.) 847-902 (Academic, London, 1976).

  3. Begun, D. J. & Aquadro, C. F. Nature 356, 519–520 (1992).

    Google Scholar 

  4. Charlesworth, B., Morgan, M. T. & Charlesworth, D. Genetics 134, 1289–1303 (1993).

    Google Scholar 

  5. Gillespie, J. H. Gene 205, 291–299 (1997).

    Google Scholar 

  6. Charlesworth, B. Genet. Res. 68, 131–150 (1996).

    Google Scholar 

  7. Eanes, W. F., Kirchner, M. & Yoon, J. Proc. Natl Acad. Sci. USA 90, 7475–7479 (1993).

    Google Scholar 

  8. Langley, C. H., MacDonald, J., Miyashita, N. & Aguadé, M. Proc. Natl Acad. Sci. USA 90, 1800–1803 (1993).

    Google Scholar 

  9. Hudson, R. R., Kreitman, M. & Aguadé, M. Genetics 116, 153–159 (1987).

    Google Scholar 

  10. Simonsen, K. L., Churchill, G. A. & Aquadro, C. F. Genetics 141, 413–429 (1995).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute for Cell, Animal and Population Biology, University of Edinburgh, Edinburgh, EH9 3JT, UK

    Brian Charlesworth & Deborah Charlesworth

Authors
  1. Brian Charlesworth
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Deborah Charlesworth
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Charlesworth, B., Charlesworth, D. How was the Sdic gene fixed?. Nature 400, 519–520 (1999). https://doi.org/10.1038/22922

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/22922

  • Springer Nature Limited

This article is cited by

Search

Navigation