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Ribosomal Subunits produced by Cold Sensitive Initiation of Protein Synthesis

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Abstract

Lowering the temperature of E. coli to 8° C results in an accumulation of ribosomal subunits arising from a block in initiating protein synthesis. It is likely that this explains the fact that cell division in E. coli does not occur at temperatures below 8° C.

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Authors and Affiliations

  1. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts

    HANNAH FRIEDMAN, PONZY LU & ALEXANDER RICH

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  1. HANNAH FRIEDMAN
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  2. PONZY LU
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  3. ALEXANDER RICH
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FRIEDMAN, H., LU, P. & RICH, A. Ribosomal Subunits produced by Cold Sensitive Initiation of Protein Synthesis. Nature 223, 909–913 (1969). https://doi.org/10.1038/223909a0

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