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Immunization of Mice against Ehrlich Ascites Tumour using a Hamster/Ehrlich Ascites Tumour Hybrid Cell Line

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Abstract

A hybrid of Ehrlich ascites tumour cells and polyoma-transformed hamster cells can be used to immunize mice against the Ehrlich ascites tumour. The hybrid cell is analogous to an attenuated tumour cell and this method of tumour immunization can be adapted for the detection of tumour antigens.

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Author notes

  1. L. CHEN: In receipt of a Lord Marks Fellowship awarded by the National Research Council of Israel. On study leave from the Weizmann Institute of Science, Rehovoth, Israel.

Authors and Affiliations

  1. Sir William Dunn School of Pathology, University of Oxford,

    J. F. WATKINS & L. CHEN

Authors
  1. J. F. WATKINS
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  2. L. CHEN
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WATKINS, J., CHEN, L. Immunization of Mice against Ehrlich Ascites Tumour using a Hamster/Ehrlich Ascites Tumour Hybrid Cell Line. Nature 223, 1018–1022 (1969). https://doi.org/10.1038/2231018a0

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  • DOI: https://doi.org/10.1038/2231018a0

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