Abstract
Autoradiography has revealed in a stringent strain of E. coli two compounds that seem to be involved in the inhibition of the synthesis of RNA.
Similar content being viewed by others
References
Gale, E. F., and Folkes, J. P., Biochem. J., 53, 493 (1953).
Pardee, A., and Prestidge, L., J. Bact., 71, 677 (1956).
Gros, F., and Gros, F., Exp. Cell Res., 14, 104 (1958).
Neidhardt, F. C., Bact. Rev., 30, 701 (1966).
Stent, G. S., and Brenner, S., Proc. US Nat. Acad. Sci., 47, 2005 (1961).
Alföldi, L., Stent, G., and Clowes, R., J. Mol. Biol., 5, 348 (1962).
Kurland, C. G., and Maaløe, O., J. Mol. Biol., 4, 193 (1962).
Tissières, A., Bourgeois, S., and Gros, F., J. Mol. Biol., 7, 100 (1963).
Olenick, J., and Hahn, F., Biochim. Biophys. Acta, 129, 429 (1966).
Bremer, H., Yegian, C., and Konrad, M., J. Mol. Biol., 16, 94 (1966).
Gallant, J., and Cashel, M., J. Mol. Biol., 25, 545 (1967).
Edlin, G., and Neuhard, J., J. Mol. Biol., 24, 225 (1967).
Cashel, M., and Gallant, J., J. Mol. Biol., 34, 317 (1968).
Irr, J., and Gallant, J., J. Biol. Chem. (in the press).
Neuhard, J., Randerath, E., and Randerath, K., Anal. Biochem., 13, 211 (1965).
Keller, E. B., and Zamecnik, P. C., J. Biol. Chem., 221, 45 (1965).
Allende, J. E., Munro, R., and Lipmann, F., Proc. US Nat. Acad. Sci., 51, 1211 (1964).
Conway, T. W., and Lipmann, F., Proc. US Nat. Acad. Sci., 52, 1462 (1964).
Arlinghaus, R., Shaeffer, J., and Schweet, R., Proc. US Nat. Acad. Sci., Wash., 51, 1291 (1964).
Randerath, K., Thin Layer Chromatogmphy, 230 (Academic Press, New York, 1966).
Roodyn, D., and Mandel, G., Biochim. Biophys. Acta, 41, 80 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CASHEL, M., GALLANT, J. Two Compounds implicated in the Function of the RC Gene of Escherichia coli. Nature 221, 838–841 (1969). https://doi.org/10.1038/221838a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/221838a0
- Springer Nature Limited
This article is cited by
-
ppGpp accumulation reduces the expression of the global nitrogen homeostasis-modulating NtcA regulon by affecting 2-oxoglutarate levels
Communications Biology (2023)
-
The τ of alarmone hydrolysis
Nature Chemical Biology (2023)
-
Awakening sleeper cells: a narrative review on bacterial magic spot synthetases as potential drug targets to overcome persistence
Current Genetics (2022)
-
The RelA hydrolase domain acts as a molecular switch for (p)ppGpp synthesis
Communications Biology (2021)
-
The stringent response and physiological roles of (pp)pGpp in bacteria
Nature Reviews Microbiology (2021)