Abstract
The amount of “bound water” in dense biological membranes such as human stratum corneum (keratin) can be estimated from the water desorption curves of the hydrated tissue. A distinct decrease in the rate of desorption, measured continuously with a microbalance, marks the transition between the elimination of free water and “bound water” from the tissue. The amount of “bound water” in fully hydrated stratum corneum can be as much as five times the dry weight of the tissue.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kavanau, J. L., Structure and Function in Biological Membranes, 1 (Holden Day, Inc., San Francisco, 1965).
Davies, J. T., and Rideal, E. K., Interfacial Phenomena (second ed.), (Academic Press, New York, 1963).
Scheraga, H. A., Ann. N.Y. Acad. Sci., 125, 253 (1965).
Grant, E. H., Ann. N.Y. Acad. Sci., 125, 418 (1965).
Berendsen, H. J. C., and Migchelsen, C., Ann. N.Y. Acad. Sci., 125, 365 (1965).
Depireux, J., and Williams, D., Nature, 195, 700 (1962).
Hays, R. M., and Leaf, A., J. Gen. Physiol., 45, 933 (1962).
Hempling, H. G., J. Gen. Physiol., 44, 365 (1960).
Zwolinski, B. J., Eyring, H., and Reese, C. E., J. Phys. Colloid Chem., 53, 1426 (1949).
Baxter, S., Trans. Faraday Soc., 39, 207 (1943).
Scheuplein, R. J., Biophys. J., 6, 1 (1966).
Scheuplein, R. J., J. Invest. Dermatol., 45, 334 (1965).
Wang, J. H., J. Amer. Chem. Soc., 73, 510 (1951).
Longsworth, L. G., in Electrochemistry in Biology and Medicine (edit. by Shedlovsky, T.), 243 (John Wiley and Sons, New York, 1955).
Hammond, B. R., and Stokes, R. H., Trans. Faraday Soc., 49, 890 (1953).
Crank, J., The Mathematics of Diffusion (Clarendon Press, Oxford, 1957).
Bull, H. B., J. Amer. Chem. Soc., 66, 1499 (1944).
Pauling, L., J. Amer. Chem. Soc., 67, 555 (1945).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SCHEUPLEIN, R., MORGAN, L. “Bound Water” in Keratin Membranes measured by a Microbalance Technique. Nature 214, 456–458 (1967). https://doi.org/10.1038/214456a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/214456a0
- Springer Nature Limited
This article is cited by
-
A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 2: physiological measurements
European Journal of Applied Physiology (2023)
-
Structural and barrier properties of the skin ceramide lipid bilayer: a molecular dynamics simulation study
Journal of Molecular Modeling (2019)
-
Regional variations in transepidermal water loss, eccrine sweat gland density, sweat secretion rates and electrolyte composition in resting and exercising humans
Extreme Physiology & Medicine (2013)
-
Influence of short chain ceramides and lipophilic penetration enhancers on the nano-structure of stratum corneum model membranes studied using neutron diffraction
Frontiers of Chemical Science and Engineering (2013)
-
Edible eyeballs from fish
Nature (1990)