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Isolation and Identification of 2-Aminoethyl-phosphonic Acid from Bovine Brain

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Abstract

IN the course of isolating unidentified amino-compounds from bovine brain1–3, a substance was isolated from the neutral amino-acid fraction of the trichloroacetic acid of the brain, and was identified as 2-aminoethylphosphonic acid from the results of elementary analysis, infra-red spectrography and chromatography. The occurrence of 2-aminoethylphosphonic acid in protozoa4,5 and in the sea anemone6 has been reported both in free and combined form; but its presence in the higher animals has not been reported in either form until now.

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References

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Authors and Affiliations

  1. Department of Neuropsychiatry, Osaka University Medical School, Osaka, Japan

    HIROTOSHI SHIMIZU, YASUO KAKIMOTO, TERUO NAKAJIMA, AKIRA KANAZAWA & ISAMU SANO

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  1. HIROTOSHI SHIMIZU
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  2. YASUO KAKIMOTO
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  3. TERUO NAKAJIMA
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  4. AKIRA KANAZAWA
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  5. ISAMU SANO
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SHIMIZU, H., KAKIMOTO, Y., NAKAJIMA, T. et al. Isolation and Identification of 2-Aminoethyl-phosphonic Acid from Bovine Brain. Nature 207, 1197–1198 (1965). https://doi.org/10.1038/2071197a0

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