Abstract
AN investigation of the calcium–potassium uptake of human erythrocyte ghosts demonstrated that their behaviour was qualitatively the same as a phospholipid-eholestcrol membrane model1. The membrane model's behaviour can be explained by the presence of negative fixed charge due to a particular phospholipid, phosphatidyl sorine2. Fragmented human erythrocyte ghosts behave as if they also possess negative fixed charge due to some chemical component or components. The work recorded here extends the analysis of the cation exchange properties of ghost fragments to the equilibrium between sodium and potassium at two concentrations of total salt.
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References
Mikulecky, D. C., and Tobias, J. M., J. Cell and Comp. Physiol., 64, 151 (1964).
Nash, H. A., and Tobias, J. M., Proc. U.S. Nat. Acad. Sci., 51, 476 (1964).
Sanui, H., and Pace, N., J. Cell. and Comp. Physiol., 62, 95 (1963).
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MIKULECKY, D. Sodium - Potassium Ion Exchange Equilibria for Fragmented Human Erythrocyte Ghosts. Nature 205, 706–707 (1965). https://doi.org/10.1038/205706a0
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DOI: https://doi.org/10.1038/205706a0
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