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Pancreatic Function during Hypothermia in the Isolated Canine Pancreas

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Abstract

RECENTLY, Véghelyi et al.1 have reported that pancreatic hypothermia leads to diminished pancreatic secretion and diminished enzyme output. Using the isolated denervated canine pancreas2, we have been able to perfuse the gland with a cooled perfusate and to analyse the pancreatic secretion for volume and protein output.

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References

  1. Véghelyi, P. V., Kemény, T. T., Zsinka, A. T., and Faur, N., Nature, 200, 478 (1964).

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  2. Nardi, G. L., Greep, J. M., Chambers, D. A., McCrae, C., and Skinner, D. B., Ann. Surg., 158, 830 (1963).

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  3. Grossman, M. I., The Exocrine Pancreas, Ciba Symp., 208 (Little, Brown and Co., Boston, 1962).

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Authors and Affiliations

  1. Department of Surgery, Harvard Medical School and the Surgical Services, Massachusetts General Hospital, Boston, USA

    D. A. CHAMBERS, J. M. GREEP & G. L. NARDI

Authors
  1. D. A. CHAMBERS
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  2. J. M. GREEP
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  3. G. L. NARDI
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CHAMBERS, D., GREEP, J. & NARDI, G. Pancreatic Function during Hypothermia in the Isolated Canine Pancreas. Nature 205, 89–90 (1965). https://doi.org/10.1038/205089b0

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