Abstract
IN the course of experiments on the amino-acid composition of rumen Protozoa, an unknown ninhydrin-positive substance was found by paper chromatography to be present in acid hydrolysates of the ether-ethanol soluble fraction of Protozoa. The substance was isolated in crystalline form and identified as 2-amino-ethane phosphonic acid, H2N·CH2·CH2·PO(OH)2, (synthesized by Finkelstein1, Kosolapoff2, Hackspill3 and Chavane4).
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References
Finkelstein, J., J. Amer. Chem. Soc., 68, 2397 (1946).
Kosolapoff, G. M., J. Amer. Chem. Soc., 69, 2112 (1947).
Hackspill, M. L., C. R. Acad. Sci., Paris, 224, 406 (1947).
Chavane, V., Ann. chim., 12, 4, 372 (1949).
McNaught, M. L., Owen, E. C., Henry, K. M., and Kon, S. K., Biochem. J., 56, 151 (1954).
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HORIGUCHI, M., KANDATSTU, M. Isolation of 2-Aminoethane Phosphonic Acid from Rumen Protozoa. Nature 184, 901–902 (1959). https://doi.org/10.1038/184901b0
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DOI: https://doi.org/10.1038/184901b0
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