Abstract
IN the analytical procedure1–3 for catechol amines based upon their reaction with ethylene diamine, it is commonly assumed that both epinephrine and norepinephrine form a single fluorescent derivative respectively, although Burn and Field4 have recently supported the existence, for each amine, of at least two fluorescent products. Gray and Young5, on the other hand, have failed to demonstrate more than one derivative by means of paper chromatography.
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References
Natelson, S., Lugovoy, J. K., and Pincus, J. B., Arch. Biochem., 23, 157 (1949).
Weil-Malherbe, H., and Bone, A. D., Biochem. J., 51, 311 (1952).
Weil-Malherbe, H., and Bone, A. D., Lancet, 264, 974 (1953).
Burn, G. P., and Field, E. O., Nature, 178, 542 (1956).
Gray, I., and Young, J. G., Clin. Chem., 3, 239 (1957).
Nadeau, G., and Joly, L. P., Anal. Chem., 29, 583 (1957).
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NADEAU, G., JOLY, LP. Fluorescent Derivatives obtained by the Reaction of Ethylene Diamine with Epinephrine and Norepinephrine. Nature 182, 180–181 (1958). https://doi.org/10.1038/182180a0
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DOI: https://doi.org/10.1038/182180a0
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