Abstract
IT has been shown that there are in the cervical vagus of the cat certain afferent fibres which yield a discharge of impulses a few seconds after an intravenous injection of phenyldiguanide1 or 5-hydroxytryptamine2. The normal functions of these afferents have now been investigated. Most of these afferents end in stretch receptors in the wall of the stomach; apparently this is the first description of such receptors.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Paintal, A. S., J. Physiol. (in the press).
Mott, J. C., and Paintal, A. S., Brit. J. Pharmacol., 8, 238 (1951).
Langworthy, O. R., and Ortega, L., J. Comp. Neurol., 79, 425 (1943).
Share, I., Martymrick, E., and Grossman, M. I., Amer. J. Physiol., 169, 229 (1952). Janowitz, D., and Grossman, M. I., Amer. J. Physiol., 159, 143 (1949). Grossman, M. I., and Stein, I. F., J. Applied Physiol., 1, 263 (1948).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PAINTAL, A. Impulses in Vagal Afferent Fibres from Stretch Receptors in the Stomach and their Role in the Peripheral Mechanism of Hunger. Nature 172, 1194–1195 (1953). https://doi.org/10.1038/1721194a0
Issue Date:
DOI: https://doi.org/10.1038/1721194a0
- Springer Nature Limited
This article is cited by
-
Neural signalling of gut mechanosensation in ingestive and digestive processes
Nature Reviews Neuroscience (2022)
-
Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling
Scientific Reports (2019)
-
The neural basis of homeostatic and anticipatory thirst
Nature Reviews Nephrology (2018)
-
Serotonin signalling in the gut—functions, dysfunctions and therapeutic targets
Nature Reviews Gastroenterology & Hepatology (2013)
-
Adventures in physiology: The times and life of Autar S Paintal (1925–2004)
Journal of Biosciences (2006)