Abstract
Two tridentate Schiff bases having ONS and NNS donor sequences were prepared by condensing S-benzyldithiocarbazate (NH2NHCSSCH2Ph) (SBDTC) with pyridine-2-carboxaldehyde and salicylaldehyde, respectively. Complexes of these ligands with NiII, ZnII, CrIII, CoII, CuII, and SnII were studied and characterized by elemental analyses and various physico-chemical techniques. NiII, CuII, ZnII and SnII complexes were four-coordinate while the CrIII, SrIII and CoIII complexes were six-coordinate. The ONS Schiff base was moderately active against leukemia, while its zinc, antimony and cobalt complexes were strongly active against leukemic cells with DC50 = 0.35–5.00.
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References
M.A. Ali, N.E. Ibrahim, R.J. Butcher, J.P. Jasinski, J.M. Jasinski and J.C. Bryan, Polyhedron, 17, 1803 (1998).
M.A. Ali, C.M. Haroon, M.N. Uddin, S.M. Majumder, M.T.H. Tarafder and M.A. Khair, Transition Met. Chem., 17, 133 (1992).
M.A. Ali, S.M.G. Hossain, S.M.M.H. Majumder, M.N. Uddin and M.T.H. Tarafder, Polyhedron, 6, 1653 (1987).
M.A. Ali, I. Intan-Safinar, M.M. Mackeen, S.H. El-Sharkawy, K. Takahata, H. Kanzaki and K. Kawazu, Natural Product Sciences, 4, 180 (1998).
M.A. Ali and S.E. Livingstone, Coord. Chem. Rev., 13, 101 (1974).
M.A. Ali, S.M.M.H. Majumder, R.J. Butcher, J.P. Jasinski and J.M. Jasinski, Polyhedron, 16, 2749 (1997).
M.A. Ali, K.K. Dey, M.N. Uddin, F.E. Smith, R.J. Butcher, J.P. Jasinski and J.M. Jasinski, Polyhedron, 15, 3331 (1996).
M.A. Ali, M.H. Kadir, M. Nazimuddin, S.M.M.H. Majumder, M.T.H. Tarafder and M.A. Khair, Indian J. Chem., 27A, 1064 (1988).
M.A. Ali, M. Uddin, M.N. Uddin, D.A. Chowdhury and M.T.H. Tarafder, Indian J. Chem., 25A, 238 (1986).
M.A. Ali and M.T.H. Tarafder, J. Inorg. Nucl. Chem., 39, 1785 (1977).
M.E. Hossain, M.N. Alam, J. Begum, M.A. Ali, M.N. Uddin, F.E. Smith and R.C. Hynes, Inorg. Chim. Acta, 249, 207 (1996).
Kazuo Nakamoto, Infrared Spectra of Inorganic and Coordination Compounds, 2nd Edit. Wiley-Interscience, New York, 1962.
L.J. Bellamy, The Infra-red Spectra of Complex Molecules, Chapman & Hall, London, 1975, p. 394.
M.T.H. Tarafder and M.A. Ali, Can. J. Chem., 56, 2000 (1978).
M.T.H. Tarafder and S. Roy, Indian J. Chem., 27A, 407 (1988).
M.T.H. Tarafder, Indian J. Chem., 28A, 531 (1989).
M.T.H. Tarafder, M.A.J. Miah, R.N. Bose and M.A. Ali, J. Inorg. Nucl. Chem., 43, 3151 (1981).
M.T.H. Tarafder and M. Rahim, Indian J. Chem., 28A, 1105 (1989).
A.M. Ali, M.M. Mackeen, I.I. Safinar, M. Hamid, N.H. Lajis, S.H. El-Sharkawy and M. Murakoshi, J. Ethnopharmacology, 53, 165 (1996).
T. Mosmann, J. Immunol. Meth., 65, 55 (1983).
W.J. Geary, Coord. Chem. Rev., 7, 81 (1971).
M.A. Ali and R. Bose, J. Inorg. Nucl. Chem., 39, 265 (1977).
B.N. Figgis, Introduction to Ligand Fields, Interscience, New York, NY, 1967, p. 316.
M.A. Ali, S.E. Livingstone and D.J. Phillips, Inorg. Chim. Acta, 7, 179 (1973).
S.H.H. Chaston and S.E. Livingstone, Austral. J. Chem., 20, 1079 (1967).
R.K.Y. Ho, S.E. Livingstone and T.N. Lockyer, Austral. J. Chem., 19, 1179 (1966).
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Tarafder, M.T.H., Ali, M.A., Saravanan, N. et al. Coordination chemistry and biological activity of two tridentate ONS and NNS Schiff bases derived from S-benzyldithiocarbazate. Transition Metal Chemistry 25, 295–298 (2000). https://doi.org/10.1023/A:1007044910814
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DOI: https://doi.org/10.1023/A:1007044910814