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Cell cycle activation by plant parasitic nematodes

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Abstract

Sedentary nematodes are important pests of crop plants. They are biotrophic parasites that can induce the (re)differentiation of either differentiated or undifferentiated plant cells into specialized feeding cells. This (re)differentiation includes the reactivation of the cell cycle in specific plant cells finally resulting in a transfer cell-like feeding site. For growth and development the nematodes fully depend on these cells. The mechanisms underlying the ability of these nematodes to manipulate a plant for its own benefit are unknown. Nematode secretions are thought to play a key role both in plant penetration and feeding cell induction. Research on plant-nematode interactions is hampered by the minute size of cyst and root knot nematodes, their obligatory biotrophic nature and their relatively long life cycle. Recently, insights into cell cycle control in Arabidopsis thaliana in combination with reporter gene technologies showed the differential activation of cell cycle gene promoters upon infection with cyst or root knot nematodes. In this review, we integrate the current views of plant cell fate manipulation by these sedentary nematodes and made an inventory of possible links between cell cycle activation and local, nematode-induced changes in auxin levels.

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Authors and Affiliations

  1. Laboratory of Nematology, Wageningen University, P.O. Box 8123, 6701 ES, Wageningen, Netherlands

    Aska Goverse & Johannes Helder

  2. Laboratory of Genetics, University of Gent / VIB, K.L. Ledeganckstraat 35, 9000, Gent, Belgium

    Janice de Almeida Engler & Godelieve Gheysen

  3. Laboratory of Plant Physiology, Wageningen University, Arboretumlaan 4, 6703 BD, Wageningen, Netherlands

    John Verhees & Sander van der Krol

Authors
  1. Aska Goverse
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  2. Janice de Almeida Engler
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  3. John Verhees
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  4. Sander van der Krol
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  5. Johannes Helder
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  6. Godelieve Gheysen
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Goverse, A., de Almeida Engler, J., Verhees, J. et al. Cell cycle activation by plant parasitic nematodes. Plant Mol Biol 43, 747–761 (2000). https://doi.org/10.1023/A:1006367126077

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