Abstract
Additions of 50 to 100 μg of acid-hydrolysed alginate oligosaccharides ml−1 and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oligosaccharides also promoted biomass formation but were not used as a carbon source.
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Asilonu, E., Bucke, C. & Keshavarz, T. Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides. Biotechnology Letters 22, 931–936 (2000). https://doi.org/10.1023/A:1005694415666
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DOI: https://doi.org/10.1023/A:1005694415666