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Examining Associations Between Negative Affect and Substance Use in Treatment-Seeking Samples: a Review of Studies Using Intensive Longitudinal Methods

  • Emotion and Addiction (K Morie, Section Editor)
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Abstract

Purpose of Review

Understanding dynamic relationships between negative affect and substance use disorder (SUD) outcomes, including craving, may help inform adaptive and personalized interventions. Recent studies using intensive longitudinal methods were reviewed to examine relationships between negative affect and the outcomes of either craving or substance use during and following SUD treatment.

Recent Findings

Results on associations between negative affect and craving/substance use were mixed and difficult to synthesize, given methodological differences across studies. The strength and direction of these relationships varied across outcomes, subgroups, contexts, and time course.

Summary

The current literature is mixed concerning negative affect and craving/substance use associations during and following SUD treatment. Researchers should increasingly recruit diverse individuals, for example, samples of varying racial and ethnic backgrounds and those reporting co-occurring disorders and polysubstance use. Experimental, qualitative, and person-specific methods will improve our understanding of relationships between negative affect and substance-related outcomes during SUD treatment.

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Funding

The preparation of this article was supported in part by grants from the National Institute on Alcohol Abuse and Alcoholism (F31AA029266, T32AA018108, R01AA022328, K99AA029459).

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Authors and Affiliations

  1. Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, USA

    Victoria R. Votaw, Felicia R. Tuchman & Katie Witkiewitz

  2. Center on Alcohol, Substance use, And Addictions, University of New Mexico, Albuquerque, NM, USA

    Victoria R. Votaw, Frank J. Schwebel & Katie Witkiewitz

  3. Department of Psychology, Northwestern University, Evanston, IL, USA

    Felicia R. Tuchman

  4. Department of Psychology, University of Washington, Seattle, WA, USA

    Marilyn L. Piccirillo

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  1. Victoria R. Votaw
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Correspondence to Victoria R. Votaw.

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Table 1 is an original table created by the authors of the manuscript and has not previously been published.

Conflict of Interest

Dr. Katie Witkiewitz is a member of the Alcohol Clinical Trials Initiative Workgroup; its activities were supported by Alkermes, Dicerna, Ethypharm, Lundbeck, Mitsubishi, and Otsuka in the past 36 months. The other authors have no conflict of interest to declare.

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Votaw, V.R., Tuchman, F.R., Piccirillo, M.L. et al. Examining Associations Between Negative Affect and Substance Use in Treatment-Seeking Samples: a Review of Studies Using Intensive Longitudinal Methods. Curr Addict Rep 9, 445–472 (2022). https://doi.org/10.1007/s40429-022-00441-8

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