Abstract
Nutritional supplements have differing effects on plasma levels of high-density lipoprotein cholesterol (HDL-C) and its main protein apolipoprotein A-I. Some supplements, including soy protein, phytosterols and black seed extracts, have been shown to increase HDL-C levels. Fish oil/omega-3 fatty acids have only modest effects on HDL-C, whereas cholic acid and high-dose antioxidant vitamins have been shown to down-regulate HDL-C levels.
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Disclosure
This article was adapted from the American Journal of Cardiovascular Drugs 2014;14(4):253–74 [1] by salaried employees of Adis/Springer. The preparation of this article was not supported by any external funding.
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Adis Medical Writers. Some nutritional supplements may have modest beneficial effects on lipid levels, but the effects of most are negligible. Drugs Ther Perspect 31, 133–136 (2015). https://doi.org/10.1007/s40267-015-0196-y
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DOI: https://doi.org/10.1007/s40267-015-0196-y