Abstract
The aim of this study is to assess the effect of ozone gas in the treatment of anorectal fistulae. The tip of a 20 G intravenous cannula was inserted from the fistula orifice. Medical ozone was introduced into the fistula. A total of 10 sessions of ozone gas insufflation was performed on alternate days. Treatment was considered to be successful if fistula discharge ceased and the outer fistula orifice closed; however, if discharge was continued or outer fistula orifice was open, the treatment considered to be failed. A total of 12 adult patients were included in the study. The fistula was closed in three patients (25 %), in nine patients (75 %) without closure. In one patient who had fistula closure, the fistula recurred after 2 months. Patients did not express any discomfort during ozone insufflation. There were no side effects or complications due to ozone insufflation. The success rate of ozone insufflation in anorectal fistulae closure is low.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bocci VA (2006) Scientific and medical aspects of ozone therapy: state of the art. Arch Med Res 37:425–435
Sharma M, Hudson JB (2008) Ozone gas is an effective and practical antibacterial agent. Am J Infect Control 36:359–363
Clavo B, Santana-Rodriguez N, Gutierrez D, Apodaca B, Lopez L, Febles G et al (2012) Ozone therapy in the management of enterocutaneous fistulas resulting from postsurgery abdominal/pelvic mesh placement. J Pain Symptom Manag 43:e1–e4
Bocci V (2005) Ozone: a new medical drug. Springer, Dordrecht
Uysal B, Yasar M, Ersoz N, Coskun O, Kilic A, Cayc T et al (2010) Efficacy of hyperbaric oxygen therapy and medical ozone therapy in experimental acute necrotizing pancreatitis. Pancreas 39:9–15
Erginel B, Erginel T, Aksoy B, Dokucu AI (2014) Effect of ozone therapy (OT) on healing of colonic anastomosis in a rat model of peritonitis. Balkan Med J 31:249–253
Altinel O, Demirbas S, Cakir E, Yaman H, Ozerhan IH, Duran E et al (2011) Comparison of hyperbaric oxygen and medical ozone therapies in a rat model of experimental distal colitis. Scand J Clin Lab Invest 71:185–192
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
The authors declare that they have no conflict of interest.
Financial Disclosure
The authors declared that this study has received no financial support.
Rights and permissions
About this article
Cite this article
Ozturk, A., Atalay, T., Cipe, G. et al. Ozone Treatment for Chronic Anal Fistula: It Is Not Promising. Indian J Surg 79, 308–311 (2017). https://doi.org/10.1007/s12262-016-1475-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12262-016-1475-0