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Updates in biological therapies for knee injuries: full thickness cartilage defect

  • Knee: Stem Cells (M Ferretti, Section Editor)
  • Published:
Current Reviews in Musculoskeletal Medicine Aims and scope Submit manuscript

Abstract

Full thickness cartilage defect might occur at different ages, but a focal defect is a major concern in the knee of young athletes. It causes impairment and does not heal by itself. Several techniques were described to treat symptomatic full thickness cartilage defect. Recently, several advances were described on the known techniques of microfracture, osteochondral allograft, cell therapy, and others. This article brings an update of current literature on these well-described techniques for full thickness cartilage defect.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Alexandre Pedro Nicolini, Rogerio Teixeira Carvalho, Bruno Dragone, Mario Lenza, Moises Cohen, and Mario Ferretti declare that they have no conflict of interest.

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  1. Division of Orthopaedic Surgery, Hospital Israelita Albert Einstein, Avenida Albert Einstein, 627/701 - 3 Andar/Bloco A1, Morumbi, 05651-901, São Paulo, SP, Brazil

    Alexandre Pedro Nicolini, Mario Lenza & Mario Ferretti

  2. Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo, São Paulo, SP, Brazil

    Alexandre Pedro Nicolini, Rogerio Teixeira Carvalho, Bruno Dragone, Mario Lenza, Moises Cohen & Mario Ferretti

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  1. Alexandre Pedro Nicolini
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Nicolini, A.P., Carvalho, R.T., Dragone, B. et al. Updates in biological therapies for knee injuries: full thickness cartilage defect. Curr Rev Musculoskelet Med 7, 256–262 (2014). https://doi.org/10.1007/s12178-014-9226-y

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