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Re-examining the Contributions of Faith, Meaning, and Peace to Quality of Life: a Report from the American Cancer Society’s Studies of Cancer Survivors-II (SCS-II)

  • Original Article
  • Published:
Annals of Behavioral Medicine

Abstract

Background

Prior research on spirituality in cancer survivors has often failed to distinguish the specific contributions of faith, meaning, and peace, dimensions of spiritual well-being, to quality of life (QoL), and has misinterpreted mediation analyses with these indices.

Purpose

We hypothesized a model in which faith would have a significant indirect effect on survivors’ functional QoL, mediated through meaning and/or peace.

Methods

Data were from the American Cancer Society’s Study of Cancer Survivors-II (N = 8405). Mediation analyses were conducted with the Functional Assessment of Chronic Illness Therapy–Spiritual Well-being Scale (FACIT-Sp) predicting the mental component summary (i.e., mental functioning) as well as the physical component summary (i.e., physical functioning) of the SF-36.

Results

The indirect effect of faith through meaning on mental functioning, 0.4303 (95 % CI, 0.3988, 0.4649), and the indirect effect of faith through meaning and peace on physical functioning, 0.1769 (95 % CI, 0.1505, 0.2045), were significant.

Discussion

The study findings suggest that faith makes a significant contribution to cancer survivors’ functional QoL. Should future longitudinal research replicate these findings, investigators may need to reconsider the role of faith in oncology QoL studies.

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References

  1. American Cancer Society. Cancer Treatment and Survivorship Facts & Figures 2013–2014. Atlanta, GA: American Cancer Society; 2014.

    Google Scholar 

  2. Stein KD, Syrjala KL, Andrykowski MA. Physical and psychological long-term and late effects of cancer. Cancer. 2008; 112(Suppl): 2577-2592.

    Article  PubMed  Google Scholar 

  3. Pirl WF. Evidence report on the occurrence, assessment, and treatment of depression in cancer patients. JNCI Monogr. 2004; 32: 32-39.

    Article  Google Scholar 

  4. Foster C, Wright D, Hill H, Hopkinson J, Roffe L. Psychosocial implications of living 5 years or more following a cancer diagnosis: a systematic review of the research evidence. Eur J Cancer Care (England). 2009; 18(3): 223-247.

    Article  CAS  Google Scholar 

  5. Feher S, Maly RC. Coping with breast cancer in later life: The role of religious faith. Psychooncology. 1999; 8(5): 408-416.

    Article  CAS  PubMed  Google Scholar 

  6. Silberfarb PM, Anderson KM, Rundle AC, Holland J, Cooper MR, McIntyre OR. Mood and clinical status in patients with multiple myeloma. J Clin Oncol. 1991; 9(12): 2219-2224.

    CAS  PubMed  Google Scholar 

  7. Yates JS, Mustian KM, Morrow GR, et al. Prevalence of complementary and alternative medicine use in cancer patients during treatment. Support Care Cancer. 2005; 13(10): 806-811.

    Article  PubMed  Google Scholar 

  8. Brady MJ, Peterman AH, Fitchett G, Mo M, Cella D. A case for including spirituality in quality of life measurement in oncology. Psychooncology. 1999; 8(5): 417-428.

    Article  CAS  PubMed  Google Scholar 

  9. Cotton SP, Levine EG, Fitzpatrick CM, Dold KH, Targ E. Exploring the relationship among spiritual well-being, quality of life, and psychological adjustment in women with breast cancer. Psychooncology. 1999; 8(5): 429-438.

    Article  CAS  PubMed  Google Scholar 

  10. Krupski TL, Kwan L, Fink A, Sonn GA, Maliski S, Litwin MS. Spirituality influences health related quality of life in men with prostate cancer. Psychooncology. 2006; 15(2): 121-131.

    Article  PubMed  Google Scholar 

  11. Canada AL, Parker PA, de Moor JS, Basen-Engquist K, Ramondetta LM, Cohen L. Active coping mediates the association between religion/spirituality and quality of life in ovarian cancer. Gynecol Oncol. 2006; 101(1): 102-107.

    Article  PubMed  Google Scholar 

  12. Daugherty CK, Fitchett G, Murphy PE, et al. Trusting God and medicine: spirituality in advanced cancer patients volunteering for clinical trials of experimental agents. Psychooncology. 2005; 14(2): 135-146.

    Article  PubMed  Google Scholar 

  13. Mytko JJ, Knight SJ. Body, mind and spirit: Towards the integration of religiosity and spirituality in cancer quality of life research. Psychooncology. 1999; 8(5): 439-450.

    Article  CAS  PubMed  Google Scholar 

  14. Sherman AC, Simonton S. Faith and health: Psychological perspectives. In: Plante TG, Thoresen CE, eds. Spirit, Science, and Health: How the Spiritual Mind Fuels Physical Wellness. Westport, CT, US: Praeger Publishers/Greenwood Publishing Group; 2007: 157-175.

    Google Scholar 

  15. Stefanek M, McDonald PG, Hess SA. Religion, spirituality, and cancer: Current status and methodological challenges. Psychooncology. 2005; 14(6): 450-463.

    Article  PubMed  Google Scholar 

  16. Visser A, Garssen B, Vingerhoets A. Spirituality and well-being in cancer patients: A review. Psychooncology. 2010; 19(6): 565-572.

    Article  PubMed  Google Scholar 

  17. Masters KS, Hooker SA. Religiousness/spirituality, cardiovascular disease, and cancer: Cultural integration for health research and intervention. J Consult Clin Psychol. 2013; 81(2): 206-216.

    Article  PubMed  Google Scholar 

  18. Peterman AH, Fitchett G, Brady MJ, Hernandez L, Cella D. Measuring spiritual well-being in people with cancer: The Functional Assessment of Chronic Illness Therapy-Spiritual Well-being scale (FACIT-Sp). Ann Behav Med. 2002; 24(1): 49-58.

    Article  PubMed  Google Scholar 

  19. Yanez B, Edmondson D, Stanton AL, et al. Facets of spirituality as predictors of adjustment to cancer: Relative contributions of having faith and finding meaning. J Consult Clin Psychol. 2009; 77(4): 730-741.

    Article  PubMed Central  PubMed  Google Scholar 

  20. MacKinnon DP. Introduction to Statistical Mediation Analysis. New York, NY: Lawrence Erlbaum Associates; 2008.

    Google Scholar 

  21. Edmondson D, Park CL, Blank TO, Fenster JR, Mills MA. Deconstructing spiritual well-being: existential well-being and HRQOL in cancer survivors. Psychooncology. 2008; 17(2): 161-169.

    Article  PubMed  Google Scholar 

  22. Nelson C, Jacobson CM, Weinberger MI, et al. The role of spirituality in the relationship between religiosity and depression in prostate cancer patients. Ann Behav Med. 2009; 38(2): 105-114.

    Article  PubMed Central  PubMed  Google Scholar 

  23. Park CL. Religion and meaning. In: Paloutzian RF, Park CL, eds. Handbook of the Psychology of Religion and Spirituality. New York, NY: The Guilford Press; 2005: 295-314.

    Google Scholar 

  24. Park CL, Malone MR, Suresh DP, Bliss D, Rosen RI. Coping, meaning in life, and quality of life in congestive heart failure patients. Qual Life Res. 2008; 17(1): 21-26.

    Article  PubMed  Google Scholar 

  25. Canada AL, Fitchett G, Murphy PE, et al. Racial/ethnic differences in spiritual well-being among cancer survivors. J Behav Med. 2013; 36(5): 441-453.

    Article  PubMed  Google Scholar 

  26. Canada AL, Murphy PE, Fitchett G, Peterman AH, Schover LR. A 3-factor model for the FACIT-Sp. Psychooncology. 2008; 17(9): 908-916.

    Article  PubMed  Google Scholar 

  27. Murphy PE, Canada AL, Fitchett G, et al. An examination of the three factor model and structural invariance across racial/ethnic groups for the FACIT-Sp: A report from the American Cancer Society’s Study of Cancer Survivors-II (SCS-II). Psychooncology. 2010; 19(3): 264-272.

    Article  PubMed  Google Scholar 

  28. Smith T, Stein KD, Mehta, et al. The rationale, design, and implementation of the American Cancer Society’s Studies of Cancer Survivors. Cancer. 2007; 109(1): 1-12.

    Article  PubMed  Google Scholar 

  29. Stein KD, Smith T, Kim Y, et al. The American Cancer Society’s Studies of Cancer Survivors: The largest, most diverse investigation of long-term cancer survivors so far. Cancer Nurs. 2006; 106(3 Suppl): 83-85.

    Article  Google Scholar 

  30. Ware JE, Kosinki M, Keller S. SF-36 Physical and Mental Health Summary Scales: A User’s Manual. Boston, MA: The Health Institute, New England Medical Center; 1994.

    Google Scholar 

  31. Ware JE, Sherbourne CD, The MOS. 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992; 30(6): 473-483.

    Article  PubMed  Google Scholar 

  32. Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986; 51(6): 1173-1182.

    Article  CAS  PubMed  Google Scholar 

  33. Ryu E, West SG, Sousa KH. Mediation and moderation: Testing relationships between symptom status, functional health, and quality of life in HIV patients. Multivar Behav Res. 2009; 44(2): 213-232.

    Article  Google Scholar 

  34. Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. New York, NY: Guilford Press; 2013.

    Google Scholar 

  35. Hayes AF. The PROCESS macro for SPSS and SAS. Columbus, OH: The Ohio State University. Available at http://www.processmacro.org/. Accessibility verified March 29, 2015.

  36. Preacher KJ, Hayes AF. Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav Res Methods. 2008; 40(3): 879-891.

    Article  PubMed  Google Scholar 

  37. Fritz MS, Taylor AB, MacKinnon DP. Explanation of two anomalous results in statistical mediation analysis. Multivar Behav Res. 2012; 47(1): 61-87.

    Article  Google Scholar 

  38. Park CL, Edmondson D, Hale-Smith A. Why religion? Meaning as motivation. In: Pargament KI, Exline JJ, Jones JW, eds. APA Handbook of Psychology, Religion, and Spirituality (Vol 1): Context, Theory, and Research. New York, NY: American Psychological Association; 2013: 157-171.

    Chapter  Google Scholar 

  39. Koenig HG. Religion, spirituality, and health: The research and clinical implications. Int Sch Res Network Psychiatry. 2012; 1–33.

  40. Meisenhelder JB, Chandler EN. Spirituality and health outcomes in the elderly. J Relig Health. 2002; 41(3): 243-252.

    Article  Google Scholar 

  41. Fetzer Institute/National Institute on Aging Working Group. (1999). Multidimensional Measurement of Religiousness/Spirituality for Use in Health Research. Kalamazoo, MI: The Fetzer Institute. Available at http://fetzer.org/resources/multidimensional-measurement-religiousnessspirituality-use-health-research. Accessibility verified March 29, 2015.

  42. Bredle JM, Salsman JM, Debb SM, Arnold BJ, Cella D. Spiritual well-being as a component of health-related quality of life: The Functional Assessment of Chronic Illness Therapy—Spiritual Well-Being Scale (FACIT-Sp). Relig. 2011; 2(1): 77-94.

    Article  Google Scholar 

  43. Hall DE, Meador KG, Koenig HG. Measuring religiousness in health research: Review and critique. J Relig Health. 2008; 47(2): 134-163.

    Article  PubMed  Google Scholar 

  44. Miller WR, Thoresen CE. Spirituality, religion, and health: An emerging research field. Am Psychol. 2003; 58(1): 24-35.

    Article  PubMed  Google Scholar 

  45. Oman D. Defining religion and spirituality. In: Paloutzian RF, Park CL, eds. Handbook of the Psychology of Religion and Spirituality. 2nd ed. New York, NY: The Guilford Press; 2013: 23-47.

    Google Scholar 

  46. Pargament KI, Mahoney A, Exline JJ, Jones JW, Shafranske EP. Envisioning an integrative paradigm for the psychology of religion and spirituality. In: Pargament KI, Exline JJ, Jones JW, eds. APA Handbook of Psychology, Religion, and Spirituality (Vol 1): Context, Theory, and Research. New York, NY: American Psychological Association; 2013: 3-19.

    Google Scholar 

  47. Zinnbauer BJ, Pargament KI, Scott AB. The emerging meanings of religiousness and spirituality: Problems and prospects. J Pers. 1999; 67(6): 889-919.

    Article  Google Scholar 

  48. Zinnbauer BJ, Pargament KI. Religiousness and spirituality. In: Paloutzian RF, Park RF, eds. Handbook of the Psychology of Religion and Spirituality. New York, NY: The Guilford Press; 2005: 21-42.

    Google Scholar 

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Acknowledgments

The American Cancer Society (ACS) Study of Cancer Survivors-II (SCS-II) was funded as an intramural research project conducted by the ACS Behavioral Research Center (BRC). We wish to acknowledge the cooperation and efforts of the cancer registries from the states of Arizona, California (regions 2–6), Colorado, Delaware, Illinois, Iowa, Maine, Massachusetts, Michigan, Nebraska, New Jersey, Pennsylvania, Washington, and Wyoming. We also thank the staff of the hundreds of hospitals contributing cases to the participating cancer registries; their data made this research possible. Lastly, we salute the thousands of cancer survivors, their physicians, and their loved ones who contributed to the collection of these data. The authors assume full responsibility for analyses and interpretation of these data.

Authors’ Statement of Conflict of Interest and Adherence to Ethical Standards

Authors Canada, Murphy, Fitchett, and Stein declare that they have no conflict of interest. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Canada, A.L., Murphy, P.E., Fitchett, G. et al. Re-examining the Contributions of Faith, Meaning, and Peace to Quality of Life: a Report from the American Cancer Society’s Studies of Cancer Survivors-II (SCS-II). ann. behav. med. 50, 79–86 (2016). https://doi.org/10.1007/s12160-015-9735-y

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