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Distinct Depression Symptom Trajectories over the First Year of Dialysis: Associations with Illness Perceptions

  • Original Article
  • Published:
Annals of Behavioral Medicine

Abstract

Background

Depression in the dialysis population is common, but trajectories of depression symptoms are unknown.

Purpose

This study aims to (1) examine whether different patterns of depression symptoms exist over the first year of dialysis and (2) to understand if illness perceptions are associated with observed trajectories of depression symptoms.

Method

Incident dialysis patients (n = 160) completed the Beck Depression Inventory II and the Revised Illness Perception Questionnaire soon after starting dialysis and again at 6 and 12 months. Latent class growth modelling identified distinct groups of depression symptom trajectories.

Results

Three depression trajectories were identified: “low-reducing” (62 %), “moderate-increasing” (21.8 %) and “high-reducing” (16.2 %). Higher levels of depression were associated with a poorer understanding of the illness (coherence) and perceptions that kidney failure has severe consequences and a more cyclical timeline. Beliefs that treatment controlled kidney failure decreased over time in patients with increasing depression symptoms.

Conclusion

Distinct patterns of depression symptoms are associated with illness perceptions. The potential to identify common patterns of depression symptoms may help target treatments at those most likely to benefit.

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Acknowledgements

This work was kindly supported by a joint Kidney Research UK/British Renal Society Fellowship. We wish to thank all the patients who predicated for their time and support.

Conflict of Interest

The authors have no conflict of interest to disclose

Author information

Authors and Affiliations

  1. Health Psychology Section, Psychology Department, Institute of Psychiatry, King’s College London, 5th floor Bermondsey Wing, Guy’s Campus, London Bridge, London, SE1 9RT, UK

    Joseph Chilcot Ph.D.

  2. Institute of Public Health, University of Cambridge, Cambridge, UK

    Sam Norton Ph.D.

  3. Center for Lifespan and Chronic Illness Research, University of Hertfordshire, Hertfordshire, UK

    David Wellsted Ph.D.

  4. UCL Centre for Nephrology, Royal Free Campus, University College London Medical School, London, UK

    Andrew Davenport M.D., F.R.C.P.

  5. Renal Unit, Addenbrooke’s Hospital, Cambridge, UK

    John Firth D.M., F.R.C.P.

  6. Renal Unit Lister, Hospital Stevenage and Post Graduate Medical School, University of Hertfordshire, Hertfordshire, UK

    Ken Farrington M.D., F.R.C.P.

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  1. Joseph Chilcot Ph.D.
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Correspondence to Joseph Chilcot Ph.D..

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Chilcot, J., Norton, S., Wellsted, D. et al. Distinct Depression Symptom Trajectories over the First Year of Dialysis: Associations with Illness Perceptions. ann. behav. med. 45, 78–88 (2013). https://doi.org/10.1007/s12160-012-9410-5

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