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Role of Bladder Dysfunction in Vesicoureteral Reflux

  • Pediatric Bladder Dysfunction (SJ Hodges, Section Editor)
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Abstract

Lower urinary tract dysfunction (LUTD) is associated with vesicoureteral reflux (VUR) as well as urinary tract infections (UTIs), particularly when micturition abnormalities occur in the voiding phase. The most common presenting symptoms are urinary urgency and frequency, UTI, incontinence, holding behaviors, and dysuria; many children will also have concurrent constipation. Since LUTD is associated with lower VUR resolution rates, increased rates of breakthrough UTI, and increased rates of surgical treatment failure, successful management of VUR in the setting of LUTD requires therapy for the VUR as well as concomitant management of the LUTD to maximize treatment success. LUTD treatment should be applied sequentially, beginning with behavioral modification and progressing to pharmacologic agents, biofeedback, and neuromodulation in refractory patients.

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Conflict of Interest

Christopher Cooper and Kathleen Kieran declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, RCP 3238, Iowa City, IA, 52242-1089, USA

    Kathleen Kieran & Christopher S. Cooper

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  1. Kathleen Kieran
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Correspondence to Kathleen Kieran.

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Kieran, K., Cooper, C.S. Role of Bladder Dysfunction in Vesicoureteral Reflux. Curr Bladder Dysfunct Rep 9, 197–204 (2014). https://doi.org/10.1007/s11884-014-0242-y

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