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Novel Architected Material for Cardiac Patches

  • Multiscale Experiments and Modeling in Biomaterials and Biological Materials
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Abstract

Myocardial infarction (MI) can lead to scar tissue formation and even heart failure. Cardiac patches are a promising technology to strengthen scar tissue post-MI. In this work, we introduce a novel periodic architected material (PAM) for potential use as cardiac patches to prevent aneurysm. The PAM is formed by a set of triangular architectures that rotate as stretching is applied. Using a combination of analytical, computational, and experimental methods, we analyze the mechanical aspects and design of the rotating triangles PAM. We demonstrate that this new material can produce localized deformation in the heart tissue and improve the force generation in the infarcted tissue. Furthermore, we show that the mechanical behavior of the rotating triangles PAM can be easily tuned, facilitating the match between the mechanical behavior of the myocardium and the cardiac patch.

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Acknowledgments

The authors gratefully acknowledge the financial support of the San Antonio Area Foundation, Biomedical Research Grants.

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Authors and Affiliations

  1. Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX, USA

    Juan Sebastian Rincon Tabares, Juan Camilo Velásquez, Hayden Bilbo, Hai-Chao Han & David Restrepo

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  1. Juan Sebastian Rincon Tabares
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  2. Juan Camilo Velásquez
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Rincon Tabares, J.S., Velásquez, J.C., Bilbo, H. et al. Novel Architected Material for Cardiac Patches. JOM 73, 1765–1773 (2021). https://doi.org/10.1007/s11837-021-04647-5

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