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Evaluation of HUGE equation (hematocrit, urea, gender) performance for screening chronic kidney disease in clinically stable cirrhotic patients

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Authors and Affiliations

  1. Ageing Biology Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Carlos G. Musso, Manuel Vilas & Jose Jauregui

  2. Hepatology and Transplantation Section-Internal Medicine Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Paola Casciato & Adrian Gadano

  3. Division of Family and Community Medicine and Research Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Sergio Terrasa

  4. Department of Public Health, Instituto Universitario Hospital Italiano, Buenos Aires, Argentina

    Sergio Terrasa

  5. Emergentology Unit, Hospital Nuestra Señora del Prado, Talavera de la Reina, Toledo, Spain

    Joaquin Alvarez-Gregori

  6. Division of Nephrology, Dialysis and Transplantation, University Hospital “San Giovanni di Dio e Ruggi d’Aragona”, Salerno, Italy

    Vincenzo Bellizzi

  7. Nephrology Division, Hospital Universitario de Salamanca, Salamanca, Spain

    Juan F. Macías Núñez

Authors
  1. Carlos G. Musso
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  2. Paola Casciato
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  3. Sergio Terrasa
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  4. Manuel Vilas
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  5. Jose Jauregui
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  6. Joaquin Alvarez-Gregori
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  7. Vincenzo Bellizzi
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  8. Adrian Gadano
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  9. Juan F. Macías Núñez
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Corresponding author

Correspondence to Carlos G. Musso.

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Conflict of interest

All the authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Appendix [7]

Appendix [7]

CKD diagnosis To have at least an abnormal value in one of the following parameters: GFR, urinalysis and renal ultrasound

  • Reduced GFR: a GFR value lower than the expected one secondary to aging: expected GFR = 130 − age (ml/min/1.73 m2) (Keller equation) [10]

  • Abnormal urinalysis: presence of persistent renal hematuria (>three red blood cells predominantly dysmorphic ones) and/or proteinuria (>0.2 g/day)

  • Abnormal renal ultrasound: presence of at least one of the following alterations in renal parenchyma: significant reduced size, marked asymmetry, increased parenchyma echogenicity, polycystosis and altered cortex–medulla proportion.

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Musso, C.G., Casciato, P., Terrasa, S. et al. Evaluation of HUGE equation (hematocrit, urea, gender) performance for screening chronic kidney disease in clinically stable cirrhotic patients. Int Urol Nephrol 48, 1555–1557 (2016). https://doi.org/10.1007/s11255-016-1332-x

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  • DOI: https://doi.org/10.1007/s11255-016-1332-x

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