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Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms

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Abstract

This review paper explores whether the cultivation of the genetically modified Bt-maize transformation event MON 88017, expressing the insecticidal Cry3Bb1 protein against corn rootworms (Coleoptera: Chrysomelidae), causes adverse effects to non-target organisms (NTOs) and the ecological and anthropocentric functions they provide. Available data do not reveal adverse effects of Cry3Bb1 on various NTOs that are representative of potentially exposed taxonomic and functional groups, confirming that the insecticidal activity of the Cry3Bb1 protein is limited to species belonging to the coleopteran family of Chrysomelidae. The potential risk to non-target chrysomelid larvae ingesting maize MON 88017 pollen deposited on host plants is minimal, as their abundance in maize fields and the likelihood of encountering harmful amounts of pollen in and around maize MON 88017 fields are low. Non-target adult chrysomelids, which may occasionally feed on maize MON 88017 plants, are not expected to be affected due to the low activity of the Cry3Bb1 protein on adults. Impacts on NTOs caused by potential unintended changes in maize MON 88017 are not expected to occur, as no differences in composition, phenotypic characteristics and plant-NTO interactions were observed between maize MON 88017 and its near-isogenic line.

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Acknowledgments

We thank Patrick du Jardin, Michael Meissle, Stefan Rauschen and the experts of the Environment Working Group on GMO applications of the EFSA GMO Panel for inspiring discussions that helped to develop this paper.

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Authors and Affiliations

  1. GMO Unit, European Food Safety Authority, Via Carlo Magno 1, 43126, Parma, Italy

    Yann Devos

  2. Biosafety and Biotechnology Unit, Scientific Institute of Public Health, Juliette Wytsmanstraat 14, 1050, Brussels, Belgium

    Adinda De Schrijver

  3. Department of Crop Protection, Ghent University, Coupure Links 653, 9000, Ghent, Belgium

    Patrick De Clercq

  4. Plant Protection Institute, Szent István University, Pater Károly 1, 2100, Gödöllő, Hungary

    József Kiss

  5. Agroscope Reckenholz-Tänikon Research Station ART, Reckenholzstrasse 191, 8046, Zurich, Switzerland

    Jörg Romeis

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Correspondence to Yann Devos or Adinda De Schrijver.

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Yann Devos and Adinda De Schrijver contributed equally to the work and should be considered co-first authors.

Opinions and views (if any) expressed in the present paper do not necessarily reflect those of the European Food Safety Authority (EFSA). This paper does not disclose any confidential information or data. Mention of proprietary products does not constitute an endorsement or a recommendation by EFSA for their use.

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Devos, Y., De Schrijver, A., De Clercq, P. et al. Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms. Transgenic Res 21, 1191–1214 (2012). https://doi.org/10.1007/s11248-012-9617-z

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