Abstract
Objective
This paper evaluates the effectiveness of motivational enhancement therapy plus cognitive behavioural therapy on depressive symptoms, glycosylated haemoglobin, fasting glucose, body mass index (BMI), and health-related quality of life in type II diabetes patients.
Methods
A controlled trial was conducted to compare patients who received the behavioural intervention with untreated controls on measures of health outcomes. A total of 31 intervention group participants and 30 controls were selected from patients that met the inclusion criteria from a hospital-based endocrinology outpatient department. The outcome measures including depressive symptoms, glycosylated haemoglobin, fasting glucose, BMI, and both physical and mental quality of life were collected before (T1), after (T2), and after 90 days (T3) following the intervention.
Results
The experimental group showed a significant reduction in glycosylated haemoglobin, fasting glucose, and depressive symptoms and a significant increase in physical quality of life and mental quality of life at T2 and T3, while patients in the control group with usual care showed no changes over time.
Conclusion
The behavioural intervention facilitated a significant improvement in psychological adjustment and glycemic control, thus strengthening diabetes control skills and leading to healthy outcomes. It is feasible that nurses and psychiatrists can deliver the behavioural intervention for diabetes patients to decrease their depressive symptoms. Sharing discussion and problem-solving experiences is particularly helpful method for self-control, and these will be beneficially influential on further research.
Similar content being viewed by others
References
Huang, C. Y., Susan, V. T., Chen, H. F., Tu, S. Y., Chang, C. J., & Pan, I. J. (2007). Stressors, depressive symptoms, and learned resourcefulness among Taiwanese adults with diabetes mellitus. Research and Theory for Nursing Practice: An International Journal, 21(2), 11–26.
Huang, C. Y., Lai, H. L., Lu, Y. C., Chi, S. C., Chen, W. K., Lu, C. Y., & Chen, C. I. (2015). Risk factors and coping affect health outcomes in adults with type 2 diabetes. Biological Research for Nursing. doi:10.1177/1099800415569845.
Bogner, H. R., Morales, K. H., de Vries, H. F., & Cappola, A. R. (2012). Integrated management of type 2 diabetes mellitus and depression treatment to improve medication adherence: A randomized controlled trial. The Annals of Family Medicine, 10(1), 15–22. doi:10.1370/afm.1344.
Egede, L. E., & Ellis, C. (2010). The effects of depression on metabolic control and quality of life in indigent patients with type 2 diabetes. Diabetes Technology & Therapeutics, 12(4), 257–262. doi:10.1089/dia.2009.0143.
Mc Sharry, J., Bishop, F. L., Moss-Morris, R., & Kendrick, T. (2013). ‘The chicken and egg thing’: Cognitive representations and self-management of multimorbidity in people with diabetes and depression. Psychology & Health, 28(1), 103–119.
Bajaj, S., Agarwal, S. K., Varma, A., & Singh, V. K. (2012). Association of depression and its relation with complications in newly diagnosed type 2 diabetes. Indian Journal of Endocrinology and Metabolism, 16(5), 759–763.
Lin, E. H. B., Rutter, C. M., Katon, W., Heckbert, S. R., Ciechanowski, P., Oliver, M. M., et al. (2009). Depression and advanced complications of diabetes: A prospective cohort study. Diabetes Care, 33(2), 264–269. doi:10.2337/dc09-1068.
van Steenbergen-Weijenburg, K. M., van Puffelen, A. L., Horn, E. K., Nuyen, J., van Dam, P. S., van Benthem, T. B., et al. (2011). More co-morbid depression in patients with Type 2 diabetes with multiple complications. An observational study at a specialized outpatient clinic. Diabetic Medicine: A Journal of the British Diabetic Association, 28(1), 86–89.
Huang, C. Y., Perng, S. J., Chen, H. F., & Lai, C. Y. (2008). The impact of learned resourcefulness on quality of life in type II diabetic patients: A cross-sectional correlational study. The Journal of Nursing Research, 16(4), 264–274.
Rotella, F., & Mannucci, E. (2013). Diabetes mellitus as a risk factor for depression. A meta-analysis of longitudinal studies. Diabetes Research and Clinical Practice, 99(2), 98–104. doi:10.1016/j.diabres.2012.11.022.
Shah, B. M., Gupchup, G. V., Borrego, M. E., Raisch, D. W., & Knapp, K. K. (2012). Depressive symptoms in patients with type 2 diabetes mellitus: do stress and coping matter? Stress Health, 28(2), 111–122. doi:10.1002/smi.1410.
Schram, M. T., Baan, C. A., & Pouwer, F. (2009). Depression and quality of life in patients with diabetes: A systematic review from the European depression in diabetes (EDID) research consortium. Current Diabetes Reviews, 5(2), 112–119.
Polonsky, W. (2002). Emotional and quality-of-life aspects of diabetes management. Current Diabetes Report, 2(2), 153–159.
Ismail, K., Thomas, S. M., Maissi, E., Chalder, T., Schmidt, U., Bartlett, J., et al. (2008). Motivational enhancement therapy with and without cognitive behavior therapy to treat type 1 diabetes: A randomized trial. Annals of Internal Medicine, 149(10), 708–719.
Minet, L., Moller, S., Vach, W., Wagner, L., & Henriksen, J. E. (2010). Mediating the effect of self-care management intervention in type 2 diabetes: A meta-analysis of 47 randomised controlled trials. Patient Education and Counseling, 80(1), 29–41. doi:10.1016/j.pec.2009.09.033.
Welschen, L., Oppen, P., Bot, S., Kostense, P., Dekker, J., & Nijpels, G. (2013). Effects of a cognitive behavioural treatment in patients with type 2 diabetes when added to managed care: A randomised controlled trial. Journal of Behavioral Medicine, 36, 556–566. doi:10.1007/s10865-012-9451-z.
Deakin, T., McShane, C. E., Cade, J. E., & Williams, R. D. (2005). Group based training for self-management strategies in people with type 2 diabetes mellitus. Cochrane Database of Systematic Reviews, 18(2), D003417. doi:10.1002/14651858.CD003417.pub2.
Duke, S. A., Colagiuri, S., & Colagiuri, R. (2009). Individual patient education for people with type 2 diabetes mellitus. Cochrane Database of Systematic Reviews., 21(1), CD005268. doi:10.1002/14651858.CD005268.pub2.
Winkley, K., Ismail, K., Landau, S., & Eisler, I. (2006). Psychological interventions to improve glycaemic control in patients with type 1 diabetes: Systematic review and meta-analysis of randomised controlled trials. British Medical Journal, 333(7558), 65.
Petrak, F., Herpertz, S., Albus, C., Hermanns, N., Hiemke, C., Hiller, W., et al. (2013). Study protocol of the Diabetes and Depression Study (DAD): A multi-center randomised controlled trial to compare the efficacy of a diabetes-specific cognitive behavioral group therapy versus sertraline in patients with major depression and poorly controlled diabetes mellitus. BMC Psychiatry, 13, 206. doi:10.1186/1471-244x-13-206.
Safren, S. A., Gonzalez, J. S., Wexler, D. J., Psaros, C., Delahanty, L. M., Blashill, A. J., et al. (2013). A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in patients with uncontrolled type 2 diabetes. Diabetes Care. doi:10.2337/dc13-0816.
Welschen, L. M., van Oppen, P., Dekker, J. M., Bouter, L. M., Stalman, W. A., & Nijpels, G. (2007). The effectiveness of adding cognitive behavioural therapy aimed at changing lifestyle to managed diabetes care for patients with type 2 diabetes: Design of a randomised controlled trial. BMC Public Health, 7, 74. doi:10.1186/1471-2458-7-74.
De Greef, K., Deforche, B., Tudor-Locke, C., & De Bourdeaudhuij, I. (2010). A cognitive-behavioural pedometer-based group intervention on physical activity and sedentary behaviour in individuals with type 2 diabetes. Health Education Research, 25(5), 724–736. doi:10.1093/her/cyq017.
Enns, M. W., Cox, B. J., & Pidlubny, S. R. (2002). Group cognitive behaviour therapy for residual depression: Effectiveness and predictors of response. Cognitive Behaviour Therapy, 31(1), 31–40.
Moher, D., Schulz, K. F., & Altman, D. G. (2001). The CONSORT statement: Revised commendations for improving the quality of reports of parallel-group randomized trials. Lancet, 357(9263), 1191–1194.
Lazarus, R. S., & Folkman, S. (1984). Stress, appraisal and coping. New York: Spring Publishing Company.
Miller, W. R., & Rollnick, S. (1991). Motivational interviewing: Preparing people to change addictive behavior. New York: Guilford Press.
Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1(3), 385–401.
Ware, J. E, Jr, & Sherbourne, C. D. (1992). The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical Care, 30(6), 473–483.
McHorney, C. A., Ware, J. E, Jr, & Raczek, A. E. (1993). The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Medical Care, 31(3), 247–263.
Huang, C. Y., Liao, L. C., Tong, K. M., Lai, H. L., Chen, W. K., Chen, C. I., et al. (2015). Mediating effects on health related quality of life in adults with osteoporosis: A structural equation modeling. Osteoporosis International, 26(3), 875–883. doi:10.1007/s00198-014-2963-3.
Nabuurs-Franssen, M. H., Huijberts, M. S. P., Kruseman, A. C. N., Willems, J., & Schaper, N. C. (2005). Health-related quality of life of diabetic foot ulcer patients and their caregivers. Diabetologia, 48(9), 1906–1910. doi:10.1007/s00125-005-1856-6.
Chatfield, M. D., Brayne, C. E., & Matthews, F. E. (2005). A systematic literature review of attrition between waves in longitudinal studies in the elderly shows a consistent pattern of dropout between differing studies. Journal of Clinical Epidemiology, 58(1), 13–19. doi:10.1016/j.jclinepi.2004.05.006.
Cohen-Mansfield, J., Parpura-Gill, A., Campbell-Kotler, M., Vass, J., & Rosenberg, F. R. (2005). Elderly persons’ preferences for topics of discussion and shared interest groups. Journal of Gerontological Social Work, 44(3–4), 39–57. doi:10.1300/J083v44n03_04.
Acknowledgments
The authors would like to thank the National Science Council for funding this research (NSC 99-2314-B-214-006-MY3-3), the participants for their contribution, and health professionals for their involvement in this research.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
No conflicts of interest are declared by the authors.
Rights and permissions
About this article
Cite this article
Huang, CY., Lai, HL., Chen, CI. et al. Effects of motivational enhancement therapy plus cognitive behaviour therapy on depressive symptoms and health-related quality of life in adults with type II diabetes mellitus: a randomised controlled trial. Qual Life Res 25, 1275–1283 (2016). https://doi.org/10.1007/s11136-015-1165-6
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11136-015-1165-6