Early results of complex experimental investigations on the study of instrumental and methodological errors of diagnostics in noninvasive medical spectrophotometry are described. Physical and technical sources and factors of errors are considered for measurements using nonbiological simulation measures. It is shown that the geometric and spectral characteristics of the optical elements and photodetectors, and also selected models and data-processing algorithms in the computer software of the instruments, have the greatest effect on the diagnostic errors.
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Notes
The scatter in the readings of one instrument for multiple measurements for an SM, neglecting the scatter of the comparative readings of different instruments for the same SM.
References
D. A. Rogatkin and L. G. Lapaeva, “Prospects for development of noninvasive spectrophotometric medical diagnosis,” Med. Tekhn., No. 4, 31–36 (2003); Biomed. Eng., 37, No. 4, 217–222 (2003).
GOST R 15.013–94, System for Development and Formulation of Products for Production. Medical Products.
D. A. Rogatkin and L. G. Lapaeva, “Complex biotechnical approach to the stage of ideological-technical design of multifunctional diagnostic systems for medical noninvasive spectrophotometry,” Biomed. Radioelektr., Nos. 8–9, 89–97 (2008).
GOST R ISO 9919–99, Pulsed Medical Oximeters. Technical Requirements and Test Methods.
D. A. Rogatkin et al., “Analysis of the accuracy of clinical laser fluorescence diagnosis,” Izmer. Tekhn., No. 7, 58–61 (1998); Measur. Techn., 41, No. 7, 670–674 (1998).
R. Reif et al., “Analysis of changes in reflectance measurements on biological tissues subjected to different probe pressures,” J. Biomed. Opt., 13, No. 1, 010502(3) (2008).
B. W. Pogue and M. S. Patterson, “Review of tissue simulating phantoms for optical spectroscopy, imaging, and dosimetry,” J. Biomed. Opt., 11, No. 4, 041102(16) (2006).
M. Pocivalnik et al., “Regional tissue oxygen saturation: comparability and reproducibility of different devices,” J. Biomed. Opt., 16, No. 1, 057004(6) (2011).
D. A. Rogatkin, A. V. Dunaev, and L. G. Lapaeva, “Metrological providing for methods and devices of noninvasive medical spectrophotometry,” Med. Tekhn., No. 2, 30–37 (2010); Biomed. Eng., 44, No. 2, 66–70 (2010).
N. I. Kolosintsyn and S. A. Kononogov, “The methodological principles of metrology,” Izmer. Tekhn., No. 8, 3–5 (2006); Measur. Techn., 49, No. 8, 741–744 (2006).
D. A. Rogatkin et al., “Multifunctional laser noninvasive spectroscopic system for medical diagnostics and metrological provisions for that,” SPIE, 7368, 7361Y (2009).
A. I. Krupatkin and V. V. Sidorov (eds.), Laser Doppler Flowmetry of Microcirculation of Blood [in Russian], Meditsina, Moscow (2005).
RMG 29-99, GSI. Metrology. Basic Terms and Definitions.
RMG 43-2001, GSI. Application of the Guide to the Expression of Uncertainty in Measurement.
GOST 8.381-80, GSI. Standards. Methods for Expression of Errors.
G. G. Rannev and A. P. Tarasenko, Methods and Measurement Devices: Textbook [in Russian], Akademiya, Moscow (2003).
A. A. Opalev and V. L. Emanuel, Fundamentals of Medical Metrology [in Russian], I. P. Pavlov SIGMU, St. Petersburg (1999).
E. G. Mironov, “A brief comparative analysis of the concepts of “error” and “uncertainty” of measurements,” Izmer. Tekhn., No. 2, 70–71 (2009); Measur. Techn., 52, No. 2, 212–214 (2009).
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Translated from Izmeritel’naya Tekhnika, No. 2, pp. 61–67, February, 2013.
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Rogatkin, D.A., Lapaeva, L.G., Bychenkov, O.A. et al. Principal Sources of Errors in Noninvasive Medical Spectrophotometry. Part 1. Physicotechnical Sources and Factors of Errors. Meas Tech 56, 201–210 (2013). https://doi.org/10.1007/s11018-013-0180-7
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DOI: https://doi.org/10.1007/s11018-013-0180-7