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Preparation of Cu (II)/PEI–QPEI/SiO2 nanopowder as antibacterial material

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Abstract

The silica nanoparticles were prepared by the sol–gel process, and then twice modified and grafted by polyethylenimine (PEI) on their surface. After quaternary ammonium reaction and chelated copper reaction, the PEI/SiO2, QPEI/SiO2, PEI–QPEI/SiO2 and Cu (II)/PEI–QPEI/SiO2 nanopowders were obtained in turn. The morphology and structure of the products were characterized through SEM, EDX, HRTEM, FTIR and element analysis. At the same time, the antibacterial activity of the products to E. coli and Candida were evaluated through quantification and qualitative ways, e.g. microcalorimetric method and culture dish method. The results suggested that the Cu (II)/PEI–QPEI/SiO2, a novel three-component functional nanopowder, presented the best antibacterial activity to both E. coli and Candida duo to the synergistic sterilization capability of the ammonium salt and copper ions, compared with other products. It indicated that the Cu (II)/PEI–QPEI/SiO2 nanopowder could be a novel antibacterial nanomaterial to widely application in preventing and minimizing bacteria of the organism and environment in future.

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Acknowledgments

The work was financially supported by National Nature Science Foundation of China (No. 21271115), and the Laboratory Open Fund of Qufu Normal University (No. 2013SK004).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Qufu Normal University, West Jingxuan Road No.57, Qufu, 273165, Shandong, People’s Republic of China

    Yanyan Huang & Zhihong Jing

  2. Tengzhou No.2 High School, South Road of Yikang Dadao No.156, Tengzhou, 277500, Shandong, People’s Republic of China

    Shi Ma

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  1. Yanyan Huang
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  2. Shi Ma
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Correspondence to Zhihong Jing.

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Huang, Y., Ma, S. & Jing, Z. Preparation of Cu (II)/PEI–QPEI/SiO2 nanopowder as antibacterial material. J Sol-Gel Sci Technol 72, 351–358 (2014). https://doi.org/10.1007/s10971-014-3439-9

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  • DOI: https://doi.org/10.1007/s10971-014-3439-9

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