Skip to main content
Log in

Cognitive Ability is Associated with Different Outcome Trajectories in Autism Spectrum Disorders

  • Original Paper
  • Published:
Journal of Autism and Developmental Disorders Aims and scope Submit manuscript

Abstract

Variability in clinical expression and in intervention outcome has been described in autism spectrum disorder (ASD). The study examined progress after 1 and 2 years of intervention and compared the impact of baseline cognitive ability on outcome trajectories in 46 children (m = 25.5 months) with ASD. The entire group showed a gradual decrease in autism severity and increase in verbal cognitive scores. Only the low cognitive scores (DQ <70) group significantly improved in fine motor and receptive language scores. Significant gains in adaptive skills were found only for the high cognitive scores (DQ ≥70) group after 2 years of intervention. The entire group progressed with intervention, but only children with higher cognitive levels at baseline transferred their acquired socio-communication skills into daily functioning.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  • American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders—Fourth edition, text revision. Washington, DC: American Psychiatric Association.

  • Ben Itzchak, E., & Zachor, D. A. (2011). Who benefit from early intervention in autism spectrum disorder? Research in Autism Spectrum Disorders, 5(1), 345–350.

    Article  Google Scholar 

  • Ben-Itzchak, E., & Zachor, D. (2007). The effects of intellectual functioning and autism severity on early behavioral intervention for children with autism. Research in Developmental Disabilities, 28(3), 287–303.

    Article  PubMed  Google Scholar 

  • Ben-Itzchak, E., & Zachor, D. A. (2009). Change in autism classification with early intervention: Predictors and outcomes. Research in Autism Spectrum Disorders, 3, 967–976.

    Article  Google Scholar 

  • Cohen, H., Amerine-Dickens, M., & Smith, T. (2006). Early intensive behavioral treatment: Replication UCLA model in a community setting. Journal of Developmental and Behavioral Pediatrics, 27, 145–155.

    Article  Google Scholar 

  • Davies, G., Tenesa, A., Payton, A., Yang, J., Harris, S. E., Liewald, D., et al. (2011). Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Molecular Psychiatry, 16, 996–1005.

    Article  PubMed Central  PubMed  Google Scholar 

  • Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., et al. (2010). Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model. Pediatrics, 125, e17–e23.

    Article  PubMed  Google Scholar 

  • Eaves, L. C., & Ho, H. H. (2004). The very early identification of autism: outcome to age 4½–5. Journal of Autism and Developmental Disorders, 34(4), 367–378.

    Article  PubMed  Google Scholar 

  • Eikeseth, S., Smith, T., Jahr, E., & Eldevik, S. (2002). Intensive behavioral treatment at school for 4- to 7- year-old children with autism. Behavior Modification, 26(1), 49–68.

    Article  PubMed  Google Scholar 

  • Eikeseth, S., Smith, T., Jahr, E., & Eldevik, S. (2007). Outcome for children with autism who began intensive behavioral treatment between ages 4 and 7: A comparison controlled study. Behavior Modification, 31, 264–278.

    Article  PubMed  Google Scholar 

  • Eldevik, S., Eikeseth, S., Jahr, E., & Smith, T. (2006). Effects of low-intensity behavioral treatment for children with autism and mental retardation. Journal of Autism and Developmental Disorders, 36, 211–224.

    Article  PubMed  Google Scholar 

  • Eldevik, S., Hastings, R. P., Hughes, J. C., Jahr, E., Eikeseth, S., & Cross, S. (2010). Using individual participant data to extend the evidence base for intensive behavioral intervention for children with autism. American Journal on Intellectual and Developmental Disabilities, 115, 381–405.

    Article  PubMed  Google Scholar 

  • Eldevik, S., Hastings, R. P., Jahr, E., & Hughes, J. C. (2012). Outcomes of behavioral intervention for children with autism in mainstream preschool settings. Journal of Autism and Developmental Disorders, 42, 210–220.

    Article  PubMed Central  PubMed  Google Scholar 

  • Fernell, E., Hedvall, Å., Westerlund, J., Höglund Carlsson, L., Eriksson, M., Barnevik Olsson, M., et al. (2011). Early intervention in 208 Swedish preschoolers with autism spectrum disorder. A prospective naturalistic study. Research in Developmental Disability, 32, 2092–2101.

    Article  Google Scholar 

  • Gabriels, R. L., Hill, D. E., Pierce, R. A., & Rogers, S. J. (2001). Predictors of treatment outcome in young children with autism: A retrospective study. Autism, 5, 407–429.

    Article  PubMed  Google Scholar 

  • Gabriels, R. L., Ivers, B. J., Hill, D. E., Agnew, J. A., & McNeil, J. (2007). Stability of adaptive behaviors in middle-school children with autism spectrum disorders. Research in Autism Spectrum Disorders, 1, 291–303.

    Article  Google Scholar 

  • Gotham, K., Pickles, A., & Lord, C. (2009). Standardizing ADOS scores for a measure of severity in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(5), 693–705.

    Article  PubMed Central  PubMed  Google Scholar 

  • Grindle, C. F., Hastings, R. P., Ville, M., Hughes, J. C., Huxley, K., Kovshoff, H., et al. (2012). Outcomes of a behavioral education model for children with autism in a mainstream school setting. Behavior Modification, 36, 298–319.

    Article  PubMed  Google Scholar 

  • Hayward, D., Eikeseth, S., Gale, C., & Morgan, S. (2009). Assessing progress during treatment for young children with autism receiving intensive behavioral interventions. Autism, 13, 613–633.

    Article  PubMed  Google Scholar 

  • Howard, J. S., Sparkman, C. R., Cohen, H. G., Green, G., & Stanislaw, H. A. (2005). Comparison of intensive behavior analytic and eclectic treatments for young children with autism. Research in Developmental Disabilities, 26, 359–383.

    Article  PubMed  Google Scholar 

  • Howlin, P., Magiati, I., & Charman, T. (2009). Systematic review of early intensive behavioral interventions for children with autism. American Journal on Mental Retardation, 114, 23–41.

    Article  Google Scholar 

  • Hus, V., Gotham, K., & Lord, C. (2012). Standardizing ADOS domain scores: Separating severity of social affect and restricted and repetitive behaviors. Journal of Autism and Developmental Disorders. doi:10.1007/s10803-012-1719-1.

  • Kovshoff, H., Hastings, R. P., & Remington, B. (2011). Two-year outcomes for children with autism after the cessation of early intensive behavioral intervention. Behavior Modification, 35, 427–450.

    Article  PubMed  Google Scholar 

  • Le Couteur, A., Lord, C., & Rutter, M. (2003). The autism diagnostic interview-revised (ADI-R). Los Angeles, CA: Western Psychological Services.

    Google Scholar 

  • Leaf, R., & McEachin, J. (1999). A work in progress. Behavior management strategies and a curriculum for intensive behavioral treatment of autism. New York: DRL Books, L.L.C.

    Google Scholar 

  • Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (1999). Autism diagnostic observation schedule V generic. Los Angeles, CA: Western Psychological Services.

    Google Scholar 

  • Lovaas, O. I. (1987). Behavioral treatment and normal educational and intellectual functioning in young autistic children. Journal of Consulting and Clinical Psychology, 55, 3–9.

    Article  PubMed  Google Scholar 

  • Magiati, I., Charman, T., & Howlin, P. A. (2007). Two-year prospective follow-up of community-based early intensive behavioural intervention and specialist nursery provision for children with autism spectrum disorders. Journal of Child Psychology and Psychiatry, 4, 803–812.

    Article  Google Scholar 

  • Magiati, I., Moss, J., Charman, T., & Howlin, P. (2011). Patterns of change in children with autism spectrum disorders who received community based comprehensive interventions in their pre-school years: A seven year follow-up study. Research in Autism Spectrum Disorders, 5, 1016–1027.

    Article  Google Scholar 

  • Magiati, I., Tay, X. W., & Howlin, P. (2012). Early comprehensive behaviorally based interventions for children with autism spectrum disorders: A summary of findings from recent reviews and meta-analyses. Neuropsychiatry, 2(6), 543–570.

    Article  Google Scholar 

  • Maurice, C., Greene, G., & Luce, S. C. (1996). Behavioral intervention for young children with autism. Austin, TX: Pro-ed.

    Google Scholar 

  • Mullen, E. (1995). The Mullen scales of early learning. Circle Pines, MN: American Guidance Service.

    Google Scholar 

  • Sallows, G., & Graupner, T. (2005). Intensive behavioral treatment for children with autism. American Journal on Mental Retardation, 110, 417–438.

    Article  PubMed  Google Scholar 

  • Sparrow, S. S., Cicchetti, D. V., & Balla, D. A. (2005). Vineland-II Adaptive Behavior Scales (2nd ed.). Eagan, MN: NCS Pearson.

  • Szatmari, P., Bryson, S. E., Boyle, M. H., Streiner, D. L., & Duku, E. (2003). Predictors of outcome among high functioning children with autism and Asperger syndrome. Journal of Child Psychology and Psychiatry, 44, 520–528.

    Article  PubMed  Google Scholar 

  • Thurm, A., Lord, C., Lee, L. C., & Newschaffer, C. (2007). Predictors of language acquisition in preschool children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(9), 1721–1734.

    Article  PubMed  Google Scholar 

  • Turner, L. M., & Stone, W. L. (2007). Variability in outcome for children with an ASD diagnosis at age 2. Journal of Child Psychology and Psychiatry, 48, 793–802.

    Article  PubMed  Google Scholar 

  • Warren, Z., McPheeters, M. L., Sathe, N., Foss-Feig, J. H., Glasser, A. & Veenstra-VanderWeele, J. (2011). A systematic review of early intensive intervention for autism spectrum disorders. Pediatrics, 127, e1303–e1311.

    Google Scholar 

  • Zachor, D. A., & Ben-Itzchak, E. (2010). Treatment approach, autism severity and intervention outcomes in young children. Research in Autism Spectrum Disorders, 4(3), 425–532.

    Article  Google Scholar 

  • Zachor, D. A., Ben-Itzchak, E., Rabinovitch, A., & Lahat, E. (2007). Change in autism core symptoms. Research in Autism Spectrum Disorders, 1(4), 304–317.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ditza A. Zachor.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ben-Itzchak, E., Watson, L.R. & Zachor, D.A. Cognitive Ability is Associated with Different Outcome Trajectories in Autism Spectrum Disorders. J Autism Dev Disord 44, 2221–2229 (2014). https://doi.org/10.1007/s10803-014-2091-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10803-014-2091-0

Keywords

Navigation