Gastrointestinal Problems in Children with Autism, Developmental Delays or Typical Development
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To compare gastrointestinal (GI) problems among children with: (1) autism spectrum disorder (ASD), (2) developmental delay (DD) and (3) typical development (TD), GI symptom frequencies were obtained for 960 children from the CHildhood Autism Risks from Genetics and Environment (CHARGE) study. We also examined scores on five Aberrant Behavior Checklist (ABC) subscales comparing ASD children with high versus low frequency GI symptoms. Compared to TD children, those with ASD [aOR 7.92 (4.89–12.85)] and DD [aOR 4.55 (2.51–8.24)] were more likely to have at least one frequent GI symptom. Restricting to ASD children, those with frequent abdominal pain, gaseousness, diarrhea, constipation or pain on stooling scored worse on irritability, social withdrawal, stereotypy, and hyperactivity compared with children having no frequent GI symptoms. Frequent GI problems affect young children with ASD and DD more commonly than those with TD. Maladaptive behaviors correlate with GI problems, suggesting these comorbidities require attention.
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- Gastrointestinal Problems in Children with Autism, Developmental Delays or Typical Development
Journal of Autism and Developmental Disorders
Volume 44, Issue 5 , pp 1117-1127
- Cover Date
- Print ISSN
- Online ISSN
- Springer US
- Additional Links
- Gastrointestinal problems
- Developmental delays
- Maladaptive behaviors
- Industry Sectors
- Author Affiliations
- 1. Department of Public Health Sciences, University of California, Davis, 1616 DaVinci Ct, Davis, CA, 95618, USA
- 2. UC CalFresh Nutrition Education Program, State Office, University of California, Davis, 1103 Meyer Hall, Davis, CA, 95616, USA
- 3. Department of Pediatrics, School of Medicine, University of California, Davis, Davis, CA, USA
- 4. Medical Investigations of Neurodevelopmental Disorders (MIND) Institute, University of California, Davis, Davis, CA, 95616, USA
- 5. Division of Environmental and Occupational Health, Department of Public Health Sciences, University of California, Davis, Davis, CA, USA