Correction to: Plumbagin Prevents IL-1β-Induced Inflammatory Response in Human Osteoarthritis Chondrocytes and Prevents the Progression of Osteoarthritis in Mice

Correction to: Inflammation

https://doi.org/10.1007/s10753-017-0530-8

The original version of this article contained mistakes, and the authors would like to correct them. The correct details are given below:

• 1. In Fig. 3c, the Western blotting pictures were used incorrectly. This is our mistake. The corrected Fig. 3c is shown in the next page.

• 2. In Fig. 5, the immunofluorescence results of control group were used incorrectly. The corrected Fig. 5 is shown in the next page.

• 3. In Fig. 6a, the Western blotting of p-IKB was used incorrectly. The corrected Fig. 6a is shown in the next page.

Fig. 3

Effect of plumbagin on IL-1β-induced iNOs and COX-2 expression in human OA chondrocytes. Human OA chondrocytes were pretreated for 2 h with various concentrations of plumbagin (2, 5, 10 μM) and then stimulated or not stimulated with IL-1β (10 ng/ml) for 24 h. ThemRNA expression levels of COX-2 (a) and iNOs (b) were assayed by qRT-PCR. The protein expression levels of iNOs and COX-2 were determined by Western blot and quantification analysis (c–e). The values are mean ± SD of three independent experiments. #p < 0.05 compared with the control group; *p < 0.05, **p < 0.01 compared with the IL-1β group.

Fig. 5

Effect of plumbagin on IL-1β-induced aggrecan and collagen-II degradation in human OA chondrocytes. Human OA chondrocytes were pretreated for 2 h with plumbagin (2, 5, 10 μM) and then stimulated or not stimulated with IL-1β (10 ng/ml) for 24 h. The mRNA expression levels of aggrecan (a) and collagen-II (b) were assayed by qRT-PCR. The protein expression levels of collagen-II were determined by immunofluorescence and quantification analysis (c). The values are mean ± SD of three independent experiments. #p < 0.05 compared with the control group; *p < 0.05, **p < 0.01 compared with the IL-1β group.

Fig. 6

Effect of plumbagin on IL-1β-induced NF-κB activation in human OA chondrocytes. Chondrocytes were pretreated with plumbagin (2, 5, 10 μM) for 2 h, followed by stimulation with or without IL-1β (10 ng/ml) for 1 h. The protein expression levels of p65, p-p65, IκB, and p-IκB were determined by Western blot and quantification analysis (a–c). The values are mean ± SD of three independent experiments. #p < 0.05 compared with the control group; *p < 0.05, **p < 0.01 compared with the IL-1β group.

The authors wish to apologize for these unintentional errors.