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Intragenomic bet-hedging

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Abstract

The notion of intragenomic bet-hedging is introduced by modeling a system where one locus is seen as setting the “environment” for selection in a two-locus genetic system. Using a spatially structured simulation model I show that bet-hedging alleles with a lower mean fitness and lower variance of fitness across genotypes at a different locus can go to fixation, potentially providing a mechanism for the reduction of severe heterozygote advantage.

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Authors and Affiliations

  1. Norwegian Institute for Water Research, Gaustadalléen 21, 0349, Oslo, Norway

    Jostein Starrfelt

  2. Department of Biological and Environmental Science, Laboratory of Ecological and Evolutionary Dynamics, University of Helsinki, Helsinki, Finland

    Jostein Starrfelt

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  1. Jostein Starrfelt
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Correspondence to Jostein Starrfelt.

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Starrfelt, J. Intragenomic bet-hedging. Genetica 139, 1019–1021 (2011). https://doi.org/10.1007/s10709-011-9603-z

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  • DOI: https://doi.org/10.1007/s10709-011-9603-z

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