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Synthesis of chromeno[2,3-b]chromenes from 2-dimethylaminophenols and malononitrile

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Chemistry of Heterocyclic Compounds Aims and scope

5a-Amino-5aH,11H-chromeno[2,3-b]chromene-11a(12H)-carbonitriles were synthesized from malono-nitrile and o-quinone methides, generated in situ by the thermolysis of phenolic Mannich bases in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene. It was also shown that this heterocyclic system can be obtained from 2-amino-4H-chromene-3-carbonitriles and the aforementioned o-quinone methides.

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Authors and Affiliations

  1. Samara State Technical University, 244 Molodogvardeiskaya St., Samara, 443100, Russia

    V. A. Osyanin, D. V. Osipov, D. D. Borisov & Yu. N. Klimochkin

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  1. V. A. Osyanin
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  2. D. V. Osipov
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  3. D. D. Borisov
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  4. Yu. N. Klimochkin
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Correspondence to V. A. Osyanin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 732-738, May, 2013.

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Osyanin, V.A., Osipov, D.V., Borisov, D.D. et al. Synthesis of chromeno[2,3-b]chromenes from 2-dimethylaminophenols and malononitrile. Chem Heterocycl Comp 49, 683–688 (2013). https://doi.org/10.1007/s10593-013-1298-x

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  • DOI: https://doi.org/10.1007/s10593-013-1298-x

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