Abstract
Although information about the ability of some filamentous fungi to biodegrade organophosphonates is available, the knowledge about accompanying changes in fungal metabolism is very limited. The aim of our study was to determine the utilization of the chosen, structurally diverse aminophosphonates by Aspergillus terreus (Thom), in the context of the behaviour of this fungus while growing in unfavourable conditions, namely the lack of easily available phosphates. We found that all the studied compounds were utilized by fungus as nutritive sources of phosphorus, however, their effect on the production of fungal biomass depended on their structure. We also observed an interesting change in the metabolism of A. terreus; namely the overproduction of 2,4-di-tert-butylphenol (2,4-DTBP), which is known to possess fungistatic activity. In the case of our study, the biosynthesis of this compound was induced by phosphorus starvation, caused either by the lack of that element in the medium, or the poor degradation of phosphonate.
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Acknowledgments
This work was supported by Polish Ministry of Science and Higher Education in the frame of the National Science Centre Grant No. UMO-2011/01/B/NZ9/04722. Pawel Lenartowicz is a recipient of a Ph.D. scholarship under a project funded by the European Social Fund.
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Lenartowicz, P., Kafarski, P. & Lipok, J. The overproduction of 2,4-DTBP accompanying to the lack of available form of phosphorus during the biodegradative utilization of aminophosphonates by Aspergillus terreus . Biodegradation 26, 65–76 (2015). https://doi.org/10.1007/s10532-014-9716-z
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DOI: https://doi.org/10.1007/s10532-014-9716-z