Abstract
We use the individual-level data from all available Demographic and Health Surveys (DHS) from 27 sub-Saharan African countries conducted between 2003 and 2012 (40 population-based and nationally representative surveys in total) to calculate HIV testing consent rates and HIV prevalence for each country separately, as well as for the pooled sample. The pooled sample comprised of 427,130 individuals. In most countries HIV prevalence in adults aged 45 years and above is higher than in the total population. We further show that over the past decade HIV prevalence has increased in older age groups, while it has decreased in younger ones. While the age patterns of HIV consent rates vary across the 27 countries included in our sample, analysis of the pooled sample across all countries reveals a u-shaped relationship with lowest consent rates around age 35 years and higher consent rates among younger and older people. We argue that future DHS and other population-based HIV surveys should offer HIV testing to all adults without age limits.
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References
Mills EJ, Bärnighausen T, Negin J. HIV and aging–preparing for the challenges ahead. New Engl J Med. 2012;366(14):1270–3.
Negin J, Bärnighausen T, Lundgren JD, Mills EJ. Aging with HIV in Africa: the challenges of living longer. AIDS. 2012;26(Suppl 1):S1–5.
UNAIDS. UNAIDS report on the global AIDS epidemic. Geneva: UNAIDS; 2013.
Zaidi J, Grapsa E, Tanser F, Newell ML, Bärnighausen T. Dramatic increase in HIV prevalence after scale-up of antiretroviral treatment. AIDS. 2013;27(14):2301–5.
Bärnighausen T, Tanser F, Newell ML. Lack of a decline in HIV incidence in a rural community with high HIV prevalence in South Africa, 2003-2007. AIDS Res Hum Retroviruses. 2009;25(4):405–9.
Bärnighausen T, Wallrauch C, Welte A, et al. HIV incidence in rural South Africa: comparison of estimates from longitudinal surveillance and cross-sectional cBED assay testing. PLoS ONE. 2008;3(11):e3640.
Asamoah-Odei E, Garcia Calleja JM, Boerma JT. HIV prevalence and trends in sub-Saharan Africa: no decline and large subregional differences. Lancet. 2004;364(9428):35–40.
Boerma JT, Ghys PD, Walker N. Estimates of HIV-1 prevalence from national population-based surveys as a new gold standard. Lancet. 2003;362(9399):1929–31.
Garcia-Calleja JM, Gouws E, Ghys PD. National population based HIV prevalence surveys in sub-Saharan Africa: results and implications for HIV and AIDS estimates. Sexual Transm Infect. 2006;82(Suppl 3):64–70.
ICF International. Prevalence estimates from the demographic and health surveys. Calverton: ICF International; 2012.
Braunstein SL, van de Wijgert JH, Nash D. HIV incidence in sub-Saharan Africa: a review of available data with implications for surveillance and prevention planning. AIDS Rev. 2009;11(3):140–56.
Misiri HE, Edriss A, Aalen OO, Dahl FA. Estimation of HIV incidence in Malawi from cross-sectional population-based sero-prevalence data. J Int AIDS Soc. 2012;15(1):14.
Negin J, Cumming RG. HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data. Bull World Health Organ. 2010;88(11):847–53.
Wallrauch C, Bärnighausen T, Newell ML. HIV prevalence and incidence in people 50 years and older in rural South Africa. S Afr Med J. 2010;100(12):812–4.
Gomez-Olive FX, Angotti N, Houle B, et al. Prevalence of HIV among those 15 and older in rural South Africa. AIDS Care. 2013;25(9):1122–8.
Harling G, Newell ML, Tanser F, Bärnighausen T. Partner age-disparity and HIV incidence risk for older women in rural South Africa. AIDS Behav. 2015;19(7):1317–26.
Harling G, Newell ML, Tanser F, Kawachi I, Subramanian SV, Bärnighausen T. Do age-disparate relationships drive HIV incidence in young women? Evidence from a population cohort in rural KwaZulu-Natal, South Africa. J Acquir Immune Defic Syndr. 2014;66(4):443–51.
Nicolosi A, Buvat J, Glasser DB, Hartmann U, Laumann EO, Gingell C. Sexual behaviour, sexual dysfunctions and related help seeking patterns in middle-aged and elderly Europeans: the global study of sexual attitudes and behaviors. World J Urol. 2006;24(4):423–8.
Nicolosi A, Laumann EO, Glasser DB, Moreira ED Jr, Paik A, Gingell C. Sexual behavior and sexual dysfunctions after age 40: the global study of sexual attitudes and behaviors. Urology. 2004;64(5):991–7.
Diokno AC, Brown MB, Herzog AR. Sexual function in the elderly. Arch Intern Med. 1990;150(1):197–200.
Lindau ST, Schumm LP, Laumann EO, Levinson W, O’Muircheartaigh CA, Waite LJ. A study of sexuality and health among older adults in the United States. New Engl J Med. 2007;357(8):762–74.
Lovejoy TI, Heckman TG, Sikkema KJ, Hansen NB, Kochman A. Changes in sexual behavior of HIV-infected older adults enrolled in a clinical trial of standalone group psychotherapies targeting depression. AIDS Behav. 2015;19(1):1–8.
Lovejoy TI, Heckman TG, Sikkema KJ, et al. Patterns and correlates of sexual activity and condom use behavior in persons 50-plus years of age living with HIV/AIDS. AIDS Behav. 2008;12(6):943–56.
Bärnighausen T, Biraro S, Bwanika J, et al. Diverse age patterns of HIV incidence rates in Africa. In: XVII International AIDS Conference, 3–8 August 2008, Mexico City; 2008.
Bor J, Herbst AJ, Newell ML, Bärnighausen T. Increases in adult life expectancy in rural South Africa: valuing the scale-up of HIV treatment. Science. 2013;339(6122):961–5.
Mills EJ, Bakanda C, Birungi J, et al. Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda. Ann Intern Med. 2011;155(4):209–16.
Hontelez JA, de Vlas SJ, Baltussen R, et al. The impact of antiretroviral treatment on the age composition of the HIV epidemic in sub-Saharan Africa. AIDS. 2012;26(Suppl 1):S19–30.
Brooks JT, Buchacz K, Gebo KA, Mermin J. HIV infection and older Americans: the public health perspective. Am J Public Health. 2012;102(8):1516–26.
Tanser F, Bärnighausen T, Grapsa E, Zaidi J, Newell ML. High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa. Science. 2013;339(6122):966–71.
Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. New Engl J Med. 2011;365(6):493–505.
Vollmer S, Alfven T, Padayachy J, Harttgen K, Ghys PD, Bärnighausen. T. HIV surveys in older adults: better data, better health. Lancet HIV. 2015; 2:e40–e41.
WHO/UNICEF/UNAIDS. Global update on HIV treatment 2013. WHO: Geneva; 2013.
Mills EJ, Rammohan A, Awofeso N. Ageing faster with AIDS in Africa. Lancet. 2011;377(9772):1131–3.
Justice AC. Commentary: treated HIV infection is a chronic disease: the case against cause of death analyses. Int J Epidemiol. 2010;39(1):146–8.
Bärnighausen T, Welz T, Hosegood V, et al. Hiding in the shadows of the HIV epidemic: obesity and hypertension in a rural population with very high HIV prevalence in South Africa. J Hum Hypertens. 2008;22(3):236–9.
Obel N, Thomsen HF, Kronborg G, et al. Ischemic heart disease in HIV-infected and HIV-uninfected individuals: a population-based cohort study. Clin Infect Dis. 2007;44(12):1625–31.
Triant VA, Lee H, Hadigan C, Grinspoon SK. Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus disease. J Clin Endocrinol Metabol. 2007;92(7):2506–12.
Chow FC, Regan S, Feske S, Meigs JB, Grinspoon SK, Triant VA. Comparison of ischemic stroke incidence in HIV-infected and non-HIV-infected patients in a US health care system. J Acquir Immune Defic Syndr. 2012;60(4):351–8.
De Wit S, Sabin CA, Weber R, et al. Incidence and risk factors for new-onset diabetes in HIV-infected patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study. Diabetes Care. 2008;31(6):1224–9.
Guimaraes MM, Greco DB, Figueiredo SM, Foscolo RB, Oliveira AR Jr, Machado LJ. High-sensitivity C-reactive protein levels in HIV-infected patients treated or not with antiretroviral drugs and their correlation with factors related to cardiovascular risk and HIV infection. Atherosclerosis. 2008;201(2):434–9.
De Luca A, de Gaetano Donati K, Colafigli M, et al. The association of high-sensitivity c-reactive protein and other biomarkers with cardiovascular disease in patients treated for HIV: a nested case-control study. BMC Infect Dis. 2013;13:414.
Cohen B, Menken J. Aging in sub-Saharan Africa: recommendation for futhering research. Washington, DC: National Academy of Sciences; 2006.
Acknowledgements
SV, KH and TB received funding for this work from UNAIDS. TB received funding from the Alexander von Humboldt Foundation through the Alexander von Humboldt professor award, and from NICHD of NIH (R01-HD084233) and NIAID of NIH (R01-AI124389 and R01-AI112339).
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This article does not contain any studies with human participants performed by any of the authors. The DHS data-collection procedures were approved by the ICF International (Calverton, MD, USA) institutional review board and by the relevant human subjects committees in each country.
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Vollmer, S., Harttgen, K., Alfven, T. et al. The HIV Epidemic in Sub-Saharan Africa is Aging: Evidence from the Demographic and Health Surveys in Sub-Saharan Africa. AIDS Behav 21 (Suppl 1), 101–113 (2017). https://doi.org/10.1007/s10461-016-1591-7
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DOI: https://doi.org/10.1007/s10461-016-1591-7