AIDS and Behavior

, Volume 18, Issue 12, pp 2409–2422

ACT2 Peer-Driven Intervention Increases Enrollment into HIV/AIDS Medical Studies Among African Americans/Blacks and Hispanics: A Cluster Randomized Controlled Trial

Authors

    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Charles M. Cleland
    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Mindy Belkin
    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Amanda Ritchie
    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Noelle Leonard
    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Marion Riedel
    • School of Social WorkColumbia University
  • Angela Banfield
    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Pablo Colon
    • Center for Drug Use and HIV ResearchNew York University College of Nursing
  • Vanessa Elharrar
    • National Institute of Allergy & Infectious Diseases National Institutes of Health
  • Jonathan Kagan
    • National Institute of Allergy & Infectious Diseases National Institutes of Health
  • Donna Mildvan
    • Division of Infectious DiseasesMt. Sinai Beth Israel Medical Center
  • ACT2 Collaborative Research Team
Original Paper

DOI: 10.1007/s10461-014-0829-5

Cite this article as:
Gwadz, M., Cleland, C.M., Belkin, M. et al. AIDS Behav (2014) 18: 2409. doi:10.1007/s10461-014-0829-5

Abstract

African American/Black and Hispanic persons living with HIV/AIDS (“AABH-PLHA”) are under-represented in HIV/AIDS medical studies (HAMS). This paper evaluates the efficacy of a social/behavioral intervention to increase rates of screening for and enrollment into HAMS in these populations. Participants (N = 540) were enrolled into a cluster randomized controlled trial of an intervention designed to overcome multi-level barriers to HAMS. Primary endpoints were rates of screening for and enrollment into therapeutic/treatment-oriented and observational studies. Intervention arm participants were 30 times more likely to be screened than controls (49.3 % vs. 3.7 %; p < .001). Half (55.5 %) of those screened were eligible for HAMS, primarily observational studies. Nine out of ten found eligible enrolled (91.7 %), almost all into observational studies (95.2 %), compared to no enrollments among controls. Achieving appropriate representation of AABH-PLHA in HAMS necessitates modification of study inclusion criteria to increase the proportion found eligible for therapeutic HAMS, in addition to social/behavioral interventions.

Keywords

Clinical trialsHIV/AIDSAfrican AmericanBlackHispanicMinorityMotivational InterviewingHealth care disparities

Copyright information

© Springer Science+Business Media New York 2014