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Evaluation of carotid artery elasticity in patients with uremia by echo tracking

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Abstract

Purpose

The purpose of this study was to compare the carotid artery wall elasticity between patients with uremia and controls using echo tracking (ET).

Methods

Ninety-three patients with uremia and 35 control subjects (Group A) were enrolled in this study. In the ET mode, the carotid artery elasticity parameters including stiffness index (β), pressure–strain elasticity modulus (EP), arterial compliance (AC), and one-point pulse wave velocity (PWVβ) were measured, and carotid intima–media thickness (IMT) was measured with B-mode ultrasonography. The patients were classified into three groups: Group B (normal IMT), Group C (thickened IMT), and Group D (one single atheroma plaque).

Results

β, EP, and PWVβ were significantly higher in Group B, C, and D (especially in group D) than those of the control group (P < 0.05), and there were significant differences between Group A and Group B, while AC was lower than in controls, but there were no statistically significant differences among the four groups.

Conclusions

ET is a noninvasive method that can demonstrate a loss in carotid artery elasticity in uremia patients with normal IMT.

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Author information

Authors and Affiliations

  1. Ultrasound Department, Beijing Zhongguancun Hospital, 12 Zhongguancun Road, Beijing, 100080, China

    Hong Liang

  2. College of Science, Harbin Engineering University, 145 Nantong Street, Harbin, 150001, China

    Dawei Wang

  3. Ultrasound Department, The Second Affiliated Hospital, Harbin Medical University, 148 Baojian Road, Harbin, 150086, China

    Guoying Che & Yanxin Su

Authors
  1. Hong Liang
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  2. Dawei Wang
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  3. Guoying Che
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  4. Yanxin Su
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Contributions

DW and HL contributed equally to this work. HL: study concepts and design/manuscript preparation. DW: clinical studies/manuscript editing. GC: experimental studies/data analysis. YS: guarantor of integrity of the entire study.

Corresponding author

Correspondence to Yanxin Su.

Ethics declarations

Ethical statements

Informed consent to the protocol was obtained from all patients and control subjects. The study was approved by our institutional ethics committee for human research.

Conflict of interest

There are no financial or other relations that could lead to a conflict of interest.

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Cite this article

Liang, H., Wang, D., Che, G. et al. Evaluation of carotid artery elasticity in patients with uremia by echo tracking. J Med Ultrasonics 45, 591–596 (2018). https://doi.org/10.1007/s10396-018-0868-z

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  • DOI: https://doi.org/10.1007/s10396-018-0868-z

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