Abstract
Purpose
The study aimed to assess the utility of ultrafast ultrasound imaging for evaluation of carotid pulse wave velocity (PWV) in newly diagnosed hypertension patients.
Methods
This prospective non-randomized study enrolled 90 hypertensive patients in our hospital from September to December 2013 as a hypertension group. An age- and sex-matched cohort of 50 healthy adults in our hospital from September to December 2013 was also included in the study as a control group. Carotid PWV at the beginning and at the end of systole (PWV-BS and PWV-ES, respectively) and intima-media thickness (IMT) were measured by ultrafast ultrasound imaging technology. The associations of PWV-BS, PWV-ES, and IMT with hypertension stage were evaluated by Spearman correlation analysis.
Results
PWV-BS and PWV-ES in the hypertension group were significantly elevated compared with those in control group. Different hypertension stages significantly differed in PWV-BS and PWV-ES. PWV-BS and PWV-ES appeared to increase with the hypertension stage. Moreover, IMT, PWV-BS, and PWV-ES were positively correlated with the hypertension stage in hypertensive patients.
Conclusion
Ultrafast ultrasound imaging was a valid and convenient method for the measurement of carotid PWV in hypertensive patients. Ultrafast ultrasound imaging might be recommended as a promising alternative method for early detection of arterial abnormality in clinical practice.
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The study was approved by the medical ethics committee of the Second Affiliated Hospital of Xi’an Jiaotong University, and written informed consent was received from each participant.
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Li, X., Jiang, J., Zhang, H. et al. Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients. J Med Ultrasonics 44, 183–190 (2017). https://doi.org/10.1007/s10396-016-0755-4
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DOI: https://doi.org/10.1007/s10396-016-0755-4