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Clinical characteristics and outcomes of open globe injuries in Japan

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery.

Study Design

Retrospective, observational, multicenter case-series study.

Methods

Patients’ data were entered into a computerized database for review and statistical analyses. The following parameters were assessed; age, gender, initial and final visual acuity, duration between onset and surgery, presence of lens in the eye, characteristics of injury, presence of ocular complications, and number of surgeries.

Results

The records of 374 eyes with OGI were enrolled. The average age of the patients was 56.8 ± 22.1 years, and the majority of patients were men (73.5%). Compared to the overall cohort, work-related OGI was the most common, associated with significantly better final visual acuity, whereas patients with fall-down OGI showed significantly worse final visual acuity (P < 0.05). Among the types of injury, both the initial and final visual acuity were significantly worse in the rupture group than in the laceration group. Multiple liner regression analyses revealed that the final visual acuity was significantly associated with initial visual acuity, type of injury (rupture), retinal detachment, and proliferative vitreoretinopathy.

Conclusion

To predict the visual outcome in patients with OGI, ophthalmologists need to pay attention not only to the initial visual acuity but also to initial ocular conditions, such as the presence of ocular complications.

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Acknowledgements

Other members of J-CREST who contributed to this study are Osamu Sawada (Japan-Clinical Research of Study (J-CREST) group; Department of Ophthalmology, Shiga University of Medical Science, Otsu, Japan), Junya Mori (Japan-Clinical Research of Study (J-CREST) group; Department of Ophthalmology, Sapporo City General Hospital, Sapporo, Japan), Yoshihiro Takamura (Japan-Clinical Research of Study (J-CREST) group; Department of Ophthalmology, Faculty of Medical Sciences University of Fukui, Yoshida-gun, Japan), Yoshinori Mitamura (Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan; Japan-Clinical Research of Study (J-CREST) group), Fumi Gomi (Department of Ophthalmology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Japan-Clinical Research of Study (J-CREST) group), Kozo Harimoto (Japan-Clinical Research of Study (J-CREST) group; Department of Ophthalmology, National Defense Medical College, Japan), Masaru Takeuchi (Japan-Clinical Research of Study (J-CREST) group; Department of Ophthalmology, National Defense Medical College, Japan), Nahoko Ogata (Department of Ophthalmology, Nara Medical University, Kashihara, Nara, Japan; Japan-Clinical Research of Study (J-CREST) group), Toshifumi Yamashita (Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan; Japan-Clinical Research of Study (J-CREST) group), Hiroki Otsuka (Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan; Japan-Clinical Research of Study (J-CREST) group), Seiji Sameshima (Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan; Japan-Clinical Research of Study (J-CREST) group), Hideki Shiihara (Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan; Japan-Clinical Research of Study (J-CREST) group), Yoshio Hirano (Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; Japan-Clinical Research of Study (J-CREST) group), Tsutomu Yasukawa (Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; Japan-Clinical Research of Study (J-CREST) group), Masahito Ohji (Japan-Clinical Research of Study (J-CREST) group; Department of Ophthalmology, Shiga University of Medical Science, Otsu, Japan), and Takamasa Kinoshita (Department of Ophthalmology, Sapporo City General Hospital, Sapporo, Japan; Department of Ophthalmology, Faculty of Medical Sciences University of Fukui, Yoshida-gun, Japan).

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan

    Yoshifumi Okamoto, Shohei Morikawa, Fumiki Okamoto & Tetsuro Oshika

  2. Department of Ophthalmology, Mito Kyodo General Hospital, Mito, Ibaraki, Japan

    Yoshifumi Okamoto

  3. Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan

    Naoki Inomoto

  4. Department of Ophthalmology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

    Hiroto Ishikawa

  5. Department of Ophthalmology, Nara Medical University, Kashihara, Nara, Japan

    Tetsuo Ueda

  6. Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan

    Taiji Sakamoto

  7. Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

    Kazuhiko Sugitani

  8. Japan-Clinical Research of Study (J-CREST) Group, Tokyo, Japan

    Yoshifumi Okamoto, Shohei Morikawa, Fumiki Okamoto, Naoki Inomoto, Hiroto Ishikawa, Tetsuo Ueda, Taiji Sakamoto, Kazuhiko Sugitani & Tetsuro Oshika

Authors
  1. Yoshifumi Okamoto
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  2. Shohei Morikawa
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  3. Fumiki Okamoto
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  4. Naoki Inomoto
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  5. Hiroto Ishikawa
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  6. Tetsuo Ueda
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  7. Taiji Sakamoto
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  8. Kazuhiko Sugitani
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  9. Tetsuro Oshika
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Contributions

Design of the study (YO, SM, FO, TO); conduct of the study (YO, SM, FO); data collection (SM, YO, NI, HI, TU, TS, KS, HO); management, analysis, and interpretation of the data (YO, SM, FO); preparation of the manuscript (YO, SM); review of the manuscript (SM, YO, FO, NI, HI, TU, TS, KS, TO); and approval of the manuscript (YO, TO). This study was approved by the Institutional Review Board at the Tsukuba University Hospital and was in adherence to the tenets of the Declaration of Helsinki.

Corresponding author

Correspondence to Yoshifumi Okamoto.

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Conflicts of interest

Y. Okamoto, None; S. Morikawa, None; F. Okamoto, None; N. Inomoto, None; H. Ishikawa, None; T. Ueda, None; T. Sakamoto, None; K. Sugitani, None; T. Oshika, None.

Additional information

The members of the Japan-Clinical Research of Study (J-CREST) Group are listed in Acknowledgements section.

Corresponding author: Yoshifumi Okamoto

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Okamoto, Y., Morikawa, S., Okamoto, F. et al. Clinical characteristics and outcomes of open globe injuries in Japan. Jpn J Ophthalmol 63, 109–118 (2019). https://doi.org/10.1007/s10384-018-0638-x

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  • DOI: https://doi.org/10.1007/s10384-018-0638-x

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